Maxi One Iron-Free
Price
Retail
$32.76
Container
90 servings
Serving
1 Capsule
Brand Quality
Why this score
Testing practices
- Lot Tested
- Third-Party Lab Tested
- Transparent Batch-Specific COAs
- ISO 17025 Lab
Testing coverage
- Identity
- Purity
- Potency
- Heavy Metals
- Raw Ingredient Testing
Certifications
- NSF Certified
- USDA Organic Certified
Manufacturing standards
- cGMP Certified
- Made in USA
Innovation
- Clinically Studied Product
Active Ingredients
- 1350 mcg
Vitamin A(1500 IU vitamin a palmitate, 3000 IU beta-carotene)
Ingredient research · Vitamin A
Vitamin A is an essential fat-soluble nutrient that enables normal vision, especially in dim light, and helps maintain immune defenses, skin and other epithelial tissues, growth, and reproduction. Supplementation can prevent or correct deficiency when intake or absorption is inadequate, benefiting visual, immune, and developmental health.
- Supports maternal and breast-milk vitamin A status, particularly where baseline stores are low.
- Supports hemoglobin response in some anemic or vitamin A-deficient populations, including when added to iron and folate.
- Supports reducing bacterial-vaginosis incidence and prevalence during pregnancy and postpartum follow-up in a studied deficient setting.
Top References
- Efect of vitamin A suplementation: a systematic review.
- Retinol-to-Fat Ratio and Retinol Concentration in Human Milk Show Similar Time Trends and Associations with Maternal Factors at the Population Level: A Systematic Review and Meta-Analysis.
- Vitamin A supplementation for postpartum women.
- Concomitant supplemental vitamin A enhances the response to weekly supplemental iron and folic acid in anemic teenagers in urban Bangladesh.
- Weekly supplementation with iron and vitamin A during pregnancy increases hemoglobin concentration but decreases serum ferritin concentration in Indonesian pregnant women.
- Maternal vitamin A and β-carotene supplementation and risk of bacterial vaginosis: a randomized controlled trial in rural Bangladesh.
- 90 mg
Vitamin C
Ingredient research · Vitamin C
Vitamin C is an essential water-soluble nutrient that supports collagen production, antioxidant defenses, and the normal function of immune cells. Supplementation reliably prevents or corrects deficiency, can improve absorption of plant-based iron, and may modestly shorten the duration of common colds when taken regularly.
- Supports lower common-cold risk during brief periods of severe physical exercise or cold stress.
- Supports circulating Vitamin C status across studied healthy and clinical populations.
- Supports short-term blood-pressure and endothelial-function outcomes in studied adults.
- Supports fasting-glucose and HbA1c outcomes in adults with type 2 diabetes.
Top References
- Vitamin C for preventing and treating the common cold.
- Effect of Dietary or Supplemental Vitamin C Intake on Vitamin C Levels in Patients with and without Cardiovascular Disease: A Systematic Review
- High-dose vitamin C supplementation increases skeletal muscle vitamin C concentration and SVCT2 transporter expression but does not alter redox status in healthy males.
- Effects of vitamin C supplementation on blood pressure: a meta-analysis of randomized controlled trials.
- Effect of vitamin C and vitamin E supplementation on endothelial function: a systematic review and meta-analysis of randomised controlled trials
- Effects of vitamin C supplementation on glycaemic control: a systematic review and meta-analysis of randomised controlled trials
- Effect of vitamin C on inflammation and metabolic markers in hypertensive and/or diabetic obese adults: a randomized controlled trial
- Supplementation of Vitamin C Reduces Blood Glucose and Improves Glycosylated Hemoglobin in Type 2 Diabetes Mellitus: A Randomized, Double-Blind Study
- 50 mcg
Vitamin D(2000 IU)
Ingredient research · Vitamin D
Vitamin D is a hormone-like nutrient that helps the body absorb calcium and maintain healthy bones and muscle function. Supplementation can reliably prevent or correct low vitamin D status, particularly when sun exposure is limited, while broader immune, cardiovascular, and metabolic benefits are less certain.
- Supports bone-density and fracture- or fall-related outcomes.
- Supports muscle-strength outcomes, including lower-limb strength.
- Supports glycemic-marker and insulin-sensitivity outcomes in studied metabolic populations.
- Supports respiratory-infection-risk outcomes across studied age groups.
Top References
- Effects of combined calcium and vitamin D supplementation on osteoporosis in postmenopausal women: a systematic review and meta-analysis of randomized controlled trials.
- What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta‐analysis
- Clinical review: The effect of vitamin D on falls: a systematic review and meta-analysis.
- Effect of Vitamin D Supplementation on Muscle Strength, Gait and Balance in Older Adults: A Systematic Review and Meta‐Analysis
- The effects of vitamin D on skeletal muscle strength, muscle mass, and muscle power: a systematic review and meta-analysis of randomized controlled trials.
- Effect of vitamin D supplementation on muscle strength: a systematic review and meta-analysis
- What is the impact of vitamin D supplementation on glycemic control in people with type-2 diabetes: a systematic review and meta-analysis of randomized controlled trails
- The Effect of Vitamin D Supplementation on Glycaemic Control in Women with Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomised Controlled Trials
- The Role of Vitamin D Oral Supplementation in Insulin Resistance in Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
- Vitamin D supplementation to prevent acute respiratory infections: individual participant data meta-analysis.
- Vitamin D supplementation to prevent acute respiratory infections: a systematic review and meta-analysis of aggregate data from randomised controlled trials.
- Vitamin D and Respiratory Tract Infections: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
- 15 mg
Vitamin E(22.4 IU D-Alpha-Tocopheryl Succinate)
Ingredient research · Vitamin E
Vitamin E is an essential fat-soluble antioxidant that protects cell membranes from oxidative damage and supports normal immune and nerve function. Supplementation is most useful for preventing or correcting deficiency, particularly when fat absorption is impaired; routine use has not shown broad protection against cardiovascular disease or cancer.
- Supports improvement in liver histology in adults without diabetes who have biopsy-confirmed nonalcoholic steatohepatitis.
- Supports lower CRP and malondialdehyde in studied adult populations, including people receiving hemodialysis.
- Supports short-term improvements in fasting glucose and HbA1c in adults with type 2 diabetes.
Top References
- Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis.
- The effect of vitamin E supplementation on selected inflammatory biomarkers in adults: a systematic review and meta-analysis of randomized clinical trials
- The effects of vitamin E supplementation on malondialdehyde as a biomarker of oxidative stress in haemodialysis patients: a systematic review and meta-analysis
- Effect of supplementation with tomato juice, vitamin E, and vitamin C on LDL oxidation and products of inflammatory activity in type 2 diabetes.
- Antioxidant effects of vitamins in type 2 diabetes: a meta-analysis of randomized controlled trials
- 20 mg
Thiamine
Ingredient research · Thiamine
Thiamine is vitamin B1, an essential nutrient that helps convert carbohydrates into usable energy and supports normal nerve and heart function. Supplementation reliably prevents or corrects deficiency, with particular relevance when absorption or intake is impaired, including in chronic heavy alcohol use.
- Supports depression-treatment response when used alongside standard antidepressant treatment.
- 20 mg
Riboflavin
Ingredient research · Vitamin B2
Vitamin B2 is riboflavin, an essential nutrient that helps enzymes release energy from food and supports normal red blood cell, skin, and nervous-system function. Supplementation reliably prevents or corrects deficiency, and regular use can reduce migraine frequency and severity in some people.
- Supports blood-pressure control in treated hypertensive adults with the MTHFR 677TT genotype.
Top References
- 20 mg
Niacin
Ingredient research · Niacin
Niacin is vitamin B3, essential for enzymes that convert food into energy and support normal skin and nervous-system function. Supplementation prevents or corrects deficiency; in high-dose nicotinic acid form it can alter cholesterol and triglycerides, but this pharmacologic use is distinct from routine nutritional supplementation.
- Supports favorable changes in selected cholesterol fractions, including LDL, HDL, and total cholesterol, in studied metabolic and diabetes populations.
- Supports favorable fasting-triglyceride changes in studied adults with diabetes or metabolic dysregulation.
Top References
- Effectiveness of niacin supplementation for patients with type 2 diabetes
- Effect of niacin on lipids and glucose in patients with type 2 diabetes: A meta-analysis of randomized, controlled clinical trials.
- Niacin induces miR-502-3p expression which impairs insulin sensitivity in human adipocytes
- Postprandial triglyceride responses to aerobic exercise and extended-release niacin.
- 20 mg
Vitamin B6
Ingredient research · Vitamin B6
Vitamin B6 is an essential nutrient that helps enzymes process amino acids and supports neurotransmitter, hemoglobin, and immune function. Supplementation reliably corrects deficiency and can reduce nausea during pregnancy; outside these uses, it is most relevant when intake or absorption is inadequate.
- Supports depressive-symptom measures in premenopausal women with hormone-related contexts.
- 400 mcg DFE
Folate(vegetarian source glucosamine salt)
Ingredient research · Folate
Folate is vitamin B9, an essential nutrient needed for DNA synthesis, cell division, and healthy red blood cell formation. Supplementation is especially important before conception and in early pregnancy because adequate folate reliably reduces neural tube defect risk, and it can also correct folate-deficiency anemia.
- Supports homocysteine measures in women with PCOS and adults with metabolic syndrome.
- Supports insulin and beta-cell-function markers in women with PCOS or cervical intraepithelial neoplasia.
- Supports selected lipid-panel and vascular markers in women with PCOS and adults with metabolic syndrome.
- Supports selected inflammation and oxidative-stress biomarkers in PCOS, metabolic syndrome, or cervical intraepithelial neoplasia.
Top References
- The effects of folate supplementation on inflammatory factors and biomarkers of oxidative stress in overweight and obese women with polycystic ovary syndrome: a randomized, double‐blind, placebo‐controlled clinical trial
- Metabolic response to folate supplementation in overweight women with polycystic ovary syndrome: a randomized double-blind placebo-controlled clinical trial.
- The Effects of Folate Supplementation on Carotid Intima-Media Thickness and Metabolic Status in Patients with Metabolic Syndrome
- Effects of long-term folate supplementation on metabolic status and regression of cervical intraepithelial neoplasia: A randomized, double-blind, placebo-controlled trial.
- 25 mcg
Vitamin B12
Ingredient research · Vitamin B12
Vitamin B12 is an essential nutrient needed for red blood cell formation, DNA synthesis, and normal nerve function. Supplementation reliably prevents or corrects deficiency—especially when intake or absorption is limited—and may improve anemia, fatigue, or neurologic symptoms caused by low B12, but is not a general energy booster when status is adequate.
- Supports vitamin B12 status and responsive deficiency markers in low-status populations, including maternal and breast-milk status during pregnancy and early lactation.
Top References
- Studies of biomarker responses to intervention with vitamin B-12: a systematic review of randomized controlled trials.
- A vitamin B-12 supplement of 500 μg/d for eight weeks does not normalize urinary methylmalonic acid or other biomarkers of vitamin B-12 status in elderly people with moderately poor vitamin B-12 status.
- Vitamin B-12 supplementation during pregnancy and early lactation increases maternal, breast milk, and infant measures of vitamin B-12 status.
- 50 mcg
Biotin
Ingredient research · Biotin
Biotin is an essential B vitamin that helps enzymes process fats, carbohydrates, and amino acids. Supplementation reliably prevents or corrects deficiency, but extra biotin has not been shown to improve hair, skin, or nails in most people who are not deficient, and high intakes can distort certain laboratory test results.
- 13 mg
Pantothenic Acid
Ingredient research · Vitamin B5
Vitamin B5 is an essential nutrient used to make coenzyme A, a molecule central to releasing energy from food and building and breaking down fats. Supplementation prevents or corrects deficiency, but deficiency is uncommon and taking extra pantothenic acid has no clearly established benefit for most otherwise well-nourished people.
- 25 mg
Calcium
Ingredient research · Calcium
Calcium is an essential mineral that gives bones and teeth their structure and also enables muscle contraction and nerve signaling. Supplements are most useful for filling inadequate intake and, often alongside vitamin D, can help preserve bone mineral density and support fracture prevention in some higher-risk groups.
- Supports bone-mineral-density outcomes in studied healthy children and older women.
- 150 mcg
Iodine
Ingredient research · Iodine
Iodine is an essential mineral the thyroid uses to make hormones that regulate metabolism, growth, and development. Supplementation reliably prevents or corrects iodine deficiency and is especially important when needs rise during pregnancy for fetal brain development, but excess intake can also disturb thyroid function.
- Supports selected micronutrient and thyroid-status markers in iodine-deficient adults.
- 50 mg
Magnesium
Ingredient research · Magnesium
Magnesium is an essential mineral that enables normal muscle and nerve function, energy production, heart rhythm, and bone maintenance. Supplements can correct low magnesium status and, depending on the formulation, may also help with constipation, muscle cramps, or migraine prevention in some people.
- 11 mg
Zinc
Ingredient research · Zinc
Zinc is an essential mineral needed for hundreds of enzymes, DNA and protein synthesis, immune defense, wound healing, and normal growth. Supplementation corrects low zinc status and helps restore these functions; certain zinc lozenges may also modestly shorten a common cold when used early, though this benefit depends on the formulation.
- 55 mcg
Selenium
Ingredient research · Selenium
Selenium is an essential trace mineral used to make antioxidant enzymes and regulate thyroid hormone activity, linking adequate intake to thyroid, immune, and reproductive function. Supplementation can correct low selenium status, but more is not necessarily better because excessive intake can be toxic.
- Supports selected thyroid-autoantibody and TSH markers in studied people with autoimmune thyroiditis.
- Supports selected antioxidant-defense biomarkers in studied metabolic, cardiovascular, and selenium-status populations.
- Supports depression-symptom measures across a small selenium-specific randomized evidence base.
Top References
- Selenium Supplementation Significantly Reduces Thyroid Autoantibody Levels in Patients with Chronic Autoimmune Thyroiditis: A Systematic Review and Meta-Analysis.
- Effect of selenium on thyroid autoimmunity and regulatory T cells in patients with Hashimoto’s thyroiditis: A prospective randomized‐controlled trial
- Effect of selenium supplementation on antioxidant markers: a systematic review and meta-analysis of randomized controlled trials
- The effect of selenium supplementation on coronary heart disease: A systematic review and meta-analysis of randomized controlled trials.
- Methods of assessment of selenium status in humans: a systematic review.
- The role of selenium in depression: a systematic review and meta-analysis of human observational and interventional studies
- 0.9 mg
Copper
Ingredient research · Copper
Copper is an essential trace mineral used by enzymes that support iron metabolism, connective-tissue formation, energy production, antioxidant defense, and nervous and immune function. Supplementation can correct low copper status and related anemia or neurologic problems, but extra copper offers no established benefit when intake and status are adequate.
- 2.3 mg
Manganese
Ingredient research · Manganese
Manganese is an essential trace mineral that activates enzymes involved in energy metabolism, connective-tissue and bone formation, and antioxidant defense. Supplementation can restore these functions when intake is inadequate or deficiency is present, but added manganese has no clear general benefit for people who already get enough.
- 100 mcg
Chromium
Ingredient research · Chromium
Chromium is a trace mineral thought to assist insulin action and the metabolism of carbohydrates, fats, and proteins. Supplements are mainly used to improve blood sugar control, though benefits are usually modest or inconsistent outside rare deficiency; the trivalent chromium in supplements is distinct from toxic industrial hexavalent chromium.
- 45 mcg
Molybdenum
Ingredient research · Molybdenum
Molybdenum is an essential trace mineral that serves as a cofactor for enzymes involved in processing sulfites, sulfur-containing amino acids and purines. Because ordinary diets generally provide enough and deficiency is exceptionally rare, standalone supplementation has no clear practical benefit for most people, though it can restore status when intake or absorption is genuinely inadequate.
- 25 mg
Choline
Ingredient research · Choline
Choline is an essential nutrient used to build cell membranes, make the neurotransmitter acetylcholine, and transport fat from the liver. Supplementation can help meet needs when dietary intake is low, with particular relevance during pregnancy and for supporting normal liver, muscle, and nervous-system function.
- 1 mg
Boron
Ingredient research · Boron
Boron is a trace element that may influence mineral metabolism and the actions of vitamin D and steroid hormones. Supplements are mainly considered for bone and joint health, but a distinct benefit in people with adequate diets has not been firmly established.
- 20 mcg
Vitamin K
Ingredient research · Vitamin K
Vitamin K is an essential fat-soluble nutrient that activates proteins needed for normal blood clotting and bone mineralization. Supplements reliably prevent or correct deficiency and may support bone health when intake or absorption is inadequate; effects beyond this, including cardiovascular benefits, are less certain and can differ between K1 and K2 forms.
- 35 mg
Energy and Vitality Blend
Ashwagandha Root Extract
Ingredient research · Ashwagandha Root Powder Extract
Ashwagandha Root Powder Extract is a concentrated preparation of the plant’s root, traditionally used to improve resilience to stress. It may modestly reduce perceived stress and anxiety and improve sleep, while possible benefits for exercise performance and male reproductive health are less consistent; effects can depend on extraction and standardization.
Bacopa Whole Plant Extract
Green Tea Leaf Extract
Ingredient research · Green Tea Leaf Extract
Green Tea Leaf Extract concentrates tea catechins, often alongside caffeine, and is mainly used for modest support of weight management and cardiometabolic health through effects on energy expenditure and fat metabolism. Its composition varies, and concentrated extracts are not equivalent to drinking green tea; some products have been linked to liver injury.
Holy Basil Leaf Extract
Ingredient research · Holy Basil Leaf Extract
Holy Basil Leaf Extract is a concentrated preparation of tulsi leaves, used as an “adaptogen” to help the body cope with stress. It may modestly support perceived stress, mood, and sleep, with possible metabolic effects, but human evidence remains limited and benefits can depend on the extract’s composition.
Pomegranate Whole Fruit Extract
Ingredient research · Pomegranate
Pomegranate is a polyphenol-rich fruit used in supplements, typically as juice concentrates or extracts, for its antioxidant and vascular effects. Pomegranate may modestly support blood pressure and blood-vessel function, with possible relevance to exercise recovery and metabolic health, though benefits depend on the preparation.
Rhodiola rosea Root Extract
Ingredient research · Rhodiola rosea root extract
Rhodiola rosea root extract is a botanical “adaptogen” used to make physical and mental strain feel more manageable. It may modestly reduce fatigue, stress-related exhaustion, or perceived effort during demanding periods, but effects depend on the extract, and distinct benefits for mood, cognition, and exercise performance remain uncertain.
Turmeric Root Extract
Ingredient research · Turmeric
Turmeric is a botanical whose curcuminoids and other compounds motivate its use for anti-inflammatory effects. Supplements, particularly standardized extracts, may modestly ease osteoarthritis-related joint pain, but whole-turmeric products are not interchangeable with isolated curcumin, and proposed digestive or metabolic benefits are less certain.
- 25 mg
Organic Whole Food Vegetable Blend
Barley Grass(organic)
Ingredient research · Barley Grass
Barley Grass is made from the young leaves of barley and is used as a concentrated source of chlorophyll, micronutrients, and plant compounds. It is often taken for antioxidant or metabolic support, but demonstrated human benefits are limited, and it should not be assumed to provide the fiber benefits of barley grain.
Cabbage(organic)
Ingredient research · Brassica oleracea
Brassica oleracea is the plant species that includes broccoli, cabbage, kale, and related vegetables, so the name alone does not identify a standardized supplement. Extracts are generally taken for glucosinolates and compounds such as sulforaphane, with interest in antioxidant and cellular-defense pathways, but their composition and demonstrated human benefits vary widely.
Parsley(organic)
Ingredient research · Parsley
Parsley is a culinary herb whose leaves contain flavonoids, carotenoids, and vitamins, while concentrated supplements are mainly taken for antioxidant, digestive, or traditional diuretic purposes. These preparations have little demonstrated human benefit beyond their nutrient content, and claims about “detox,” kidney, or urinary support remain speculative.
Chlorella(organic)
Ingredient research · Chlorella
Chlorella is a nutrient-dense freshwater microalga supplied as powders or tablets, providing protein, carotenoids, and varying amounts of vitamins and minerals. Studies suggest it may modestly benefit cholesterol, blood pressure, and glucose control, while popular detox and immune claims remain uncertain.
- Supports total- and LDL-cholesterol responses during a dietary cholesterol challenge.
Spirulina(organic)
Ingredient research · Spirulina
Spirulina is a nutrient-dense dried cyanobacterium containing protein, iron, and antioxidant pigments such as phycocyanin. Supplementation may modestly improve blood lipids and glucose control in some people, but its broader health claims are less certain, and it should not be treated as a reliable source of vitamin B12.
- Supports selected blood-lipid measures.
- Supports body weight and selected waist and body-measure outcomes.
- Supports fatigue tolerance in limited endurance-exercise settings.
- Supports selected antioxidant and oxidative-stress biomarkers.
Top References
- Quantifying the effects of spirulina supplementation on plasma lipid and glucose concentrations, body weight, and blood pressure
- The effects of spirulina on glycemic control and serum lipoproteins in patients with metabolic syndrome and related disorders: A systematic review and meta‐analysis of randomized controlled trials
- The effect of spirulina on type 2 diabetes: a systematic review and meta-analysis
- Effects of Spirulina supplementation on obesity: A systematic review and meta-analysis of randomized clinical trials.
- Spirulina supplementation and anthropometric indices: A systematic review and meta‐analysis of controlled clinical trials
- The effects of Spirulina Platensis on anthropometric indices, appetite, lipid profile and serum vascular endothelial growth factor (VEGF) in obese individuals: a randomized double blinded placebo controlled trial
- Antioxidant, anti-inflammatory and immunomodulatory effects of spirulina in exercise and sport: A systematic review
- Ergogenic and antioxidant effects of spirulina supplementation in humans.
- Effect of Arthrospira (Spirulina) maxima Supplementation and a Systematic Physical Exercise Program on the Body Composition and Cardiorespiratory Fitness of Overweight or Obese Subjects: A Double-Blind, Randomized, and Crossover Controlled Trial
- Effects of Spirulina supplementation in patients with ulcerative colitis: a double-blind, placebo-controlled randomized trial
Sea Kelp(organic)
Kale(organic)
Ingredient research · Brassica oleracea
Brassica oleracea is the plant species that includes broccoli, cabbage, kale, and related vegetables, so the name alone does not identify a standardized supplement. Extracts are generally taken for glucosinolates and compounds such as sulforaphane, with interest in antioxidant and cellular-defense pathways, but their composition and demonstrated human benefits vary widely.
Broccoli(organic)
Ingredient research · Brassica oleracea
Brassica oleracea is the plant species that includes broccoli, cabbage, kale, and related vegetables, so the name alone does not identify a standardized supplement. Extracts are generally taken for glucosinolates and compounds such as sulforaphane, with interest in antioxidant and cellular-defense pathways, but their composition and demonstrated human benefits vary widely.
Dandelion(organic)
Ingredient research · Dandelion
Dandelion is a whole botanical used in leaf- and root-based preparations, traditionally taken to increase urine flow and ease digestive complaints. Its bitter compounds and root inulin help explain interest in digestive and metabolic health, but clear clinical benefits from dandelion supplements have not been established.
Broccoli(organic)
Ingredient research · Brassica oleracea
Brassica oleracea is the plant species that includes broccoli, cabbage, kale, and related vegetables, so the name alone does not identify a standardized supplement. Extracts are generally taken for glucosinolates and compounds such as sulforaphane, with interest in antioxidant and cellular-defense pathways, but their composition and demonstrated human benefits vary widely.
Dulse(organic)
Ingredient research · Dulse Extract
Dulse Extract is a preparation of the red seaweed Palmaria palmata that may concentrate iodine, minerals, and antioxidant compounds. It is taken mainly for thyroid, antioxidant, or metabolic support, but distinct human benefits of the extract are not well established, and iodine content can vary substantially among products.
- 10 mg
Plant Source Enzyme Blend
Bromelain(2000 GDU/gram)
Ingredient research · Bromelain
Bromelain is a mixture of protein-digesting enzymes, not a single compound, whose proteolytic activity underlies its use as a digestive aid and its proposed anti-inflammatory effects. It may modestly ease swelling and discomfort following some surgeries and may benefit joint or sinus symptoms, though effects are context-dependent.
Papain
Ingredient research · Papain
Papain is a protein-digesting enzyme from papaya latex, used in supplements to help break down dietary protein and sometimes included in enzyme blends aimed at digestive comfort. Its protease activity is clear, but evidence that oral papain alone meaningfully improves digestion or broader inflammatory complaints remains limited.
Amylase
Ingredient research · Amylase
Amylase is a digestive enzyme that breaks starches into smaller sugars for absorption. As a supplement, it is usually included in digestive-enzyme blends and may aid starch digestion when natural enzyme output is impaired, but it has little established benefit as a stand-alone aid for people with normal digestion.
Cellulase
Ingredient research · Cellulase
Cellulase is an enzyme that breaks down cellulose, the structural fiber in plant cell walls, which human digestive enzymes cannot digest. It is included in some digestive-enzyme blends to help process fibrous foods and potentially reduce related fullness or gas, but distinct benefits from cellulase supplementation remain uncertain.
Glucoamylase
Ingredient research · Glucoamylase
Glucoamylase is a digestive enzyme that clips glucose units from starch fragments, complementing amylase’s earlier breakdown of complex carbohydrates. In enzyme supplements, it is intended to improve starch digestion and reduce related post-meal discomfort, though distinct benefits in people with normal digestive function are not well established.
Lipase
Ingredient research · Lipase
Lipase is a digestive enzyme that breaks dietary fats into absorbable components. Supplemental lipase is mainly intended to aid fat digestion, particularly when enzyme output is inadequate, but over-the-counter lipase alone is not equivalent to prescription pancreatic enzyme replacement and should not be understood as a fat-burning aid.
Protease
Ingredient research · Protease
Protease refers to a broad category of peptidase enzymes that split dietary proteins into smaller peptides and amino acids. In digestive-enzyme supplements, they may aid protein digestion, particularly when natural digestive capacity is impaired, but effects depend on the specific enzyme, its activity, and whether it remains active in the gut.
Ranking
Inactive Ingredients
9.6 Safe
- HypromelloseIdeal
- Water, PurifiedIdeal
- CelluloseIdeal
- Magnesium StearateSafe
- Silicon DioxideIdeal
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