Detox Antiox

• Vitamin C

  500 mg

  Ingredient research · Vitamin C

  Vitamin C is an essential water-soluble nutrient that supports collagen production, antioxidant defenses, and the normal function of immune cells. Supplementation reliably prevents or corrects deficiency, can improve absorption of plant-based iron, and may modestly shorten the duration of common colds when taken regularly.

  • Supports lower common-cold risk during brief periods of severe physical exercise or cold stress.
  • Supports circulating Vitamin C status across studied healthy and clinical populations.
  • Supports short-term blood-pressure and endothelial-function outcomes in studied adults.
  • Supports fasting-glucose and HbA1c outcomes in adults with type 2 diabetes.

  Top References

  • Vitamin C for preventing and treating the common cold.
  • Effect of Dietary or Supplemental Vitamin C Intake on Vitamin C Levels in Patients with and without Cardiovascular Disease: A Systematic Review
  • High-dose vitamin C supplementation increases skeletal muscle vitamin C concentration and SVCT2 transporter expression but does not alter redox status in healthy males.
  • Effects of vitamin C supplementation on blood pressure: a meta-analysis of randomized controlled trials.
  • Effect of vitamin C and vitamin E supplementation on endothelial function: a systematic review and meta-analysis of randomised controlled trials
  • Effects of vitamin C supplementation on glycaemic control: a systematic review and meta-analysis of randomised controlled trials
  • Effect of vitamin C on inflammation and metabolic markers in hypertensive and/or diabetic obese adults: a randomized controlled trial
  • Supplementation of Vitamin C Reduces Blood Glucose and Improves Glycosylated Hemoglobin in Type 2 Diabetes Mellitus: A Randomized, Double-Blind Study

• Vitamin E

  8 IU

  Ingredient research · Vitamin E

  Vitamin E is an essential fat-soluble antioxidant that protects cell membranes from oxidative damage and supports normal immune and nerve function. Supplementation is most useful for preventing or correcting deficiency, particularly when fat absorption is impaired; routine use has not shown broad protection against cardiovascular disease or cancer.

  • Supports improvement in liver histology in adults without diabetes who have biopsy-confirmed nonalcoholic steatohepatitis.
  • Supports lower CRP and malondialdehyde in studied adult populations, including people receiving hemodialysis.
  • Supports short-term improvements in fasting glucose and HbA1c in adults with type 2 diabetes.

  Top References

  • Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis.
  • The effect of vitamin E supplementation on selected inflammatory biomarkers in adults: a systematic review and meta-analysis of randomized clinical trials
  • The effects of vitamin E supplementation on malondialdehyde as a biomarker of oxidative stress in haemodialysis patients: a systematic review and meta-analysis
  • Effect of supplementation with tomato juice, vitamin E, and vitamin C on LDL oxidation and products of inflammatory activity in type 2 diabetes.
  • Antioxidant effects of vitamins in type 2 diabetes: a meta-analysis of randomized controlled trials

• Biotin(Biotin (Form: as D-Biotin))

  150 mcg

  Ingredient research · Biotin

  Biotin is an essential B vitamin that helps enzymes process fats, carbohydrates, and amino acids. Supplementation reliably prevents or corrects deficiency, but extra biotin has not been shown to improve hair, skin, or nails in most people who are not deficient, and high intakes can distort certain laboratory test results.

• Zinc

  15 mg

  Ingredient research · Zinc

  Zinc is an essential mineral needed for hundreds of enzymes, DNA and protein synthesis, immune defense, wound healing, and normal growth. Supplementation corrects low zinc status and helps restore these functions; certain zinc lozenges may also modestly shorten a common cold when used early, though this benefit depends on the formulation.

• Selenium(Selenium (Form: as Selenomethionine))

  100 mcg

  Ingredient research · Selenium

  Selenium is an essential trace mineral used to make antioxidant enzymes and regulate thyroid hormone activity, linking adequate intake to thyroid, immune, and reproductive function. Supplementation can correct low selenium status, but more is not necessarily better because excessive intake can be toxic.

  • Supports selected thyroid-autoantibody and TSH markers in studied people with autoimmune thyroiditis.
  • Supports selected antioxidant-defense biomarkers in studied metabolic, cardiovascular, and selenium-status populations.
  • Supports depression-symptom measures across a small selenium-specific randomized evidence base.

  Top References

  • Selenium Supplementation Significantly Reduces Thyroid Autoantibody Levels in Patients with Chronic Autoimmune Thyroiditis: A Systematic Review and Meta-Analysis.
  • Effect of selenium on thyroid autoimmunity and regulatory T cells in patients with Hashimoto’s thyroiditis: A prospective randomized‐controlled trial
  • Effect of selenium supplementation on antioxidant markers: a systematic review and meta-analysis of randomized controlled trials
  • The effect of selenium supplementation on coronary heart disease: A systematic review and meta-analysis of randomized controlled trials.
  • Methods of assessment of selenium status in humans: a systematic review.
  • The role of selenium in depression: a systematic review and meta-analysis of human observational and interventional studies

• Manganese

  3 mg

  Ingredient research · Manganese

  Manganese is an essential trace mineral that activates enzymes involved in energy metabolism, connective-tissue and bone formation, and antioxidant defense. Supplementation can restore these functions when intake is inadequate or deficiency is present, but added manganese has no clear general benefit for people who already get enough.

• Molybdenum

  100 mcg

  Ingredient research · Molybdenum

  Molybdenum is an essential trace mineral that serves as a cofactor for enzymes involved in processing sulfites, sulfur-containing amino acids and purines. Because ordinary diets generally provide enough and deficiency is exceptionally rare, standalone supplementation has no clear practical benefit for most people, though it can restore status when intake or absorption is genuinely inadequate.

• N-Acetyl-Cysteine

  250 mg

  Ingredient research · NAC

  NAC is a cysteine derivative that helps replenish glutathione, a major cellular antioxidant, and also thins mucus by breaking bonds in its proteins. As a supplement, it may support antioxidant defenses and respiratory health; acetylcysteine also has established medical uses as a mucolytic and as an antidote for acetaminophen poisoning.

  • Supports glutathione and antioxidant-defense measures.
  • Supports depressive symptoms and negative symptoms of schizophrenia.
  • Supports cannabis-use, craving, and abstinence outcomes.
  • Evidence supports kidney-function and injury-marker outcomes in clinical treatment settings.
  • Supports hearing-loss and ototoxicity outcomes in noise- and medication-exposure settings.

  Top References

  • N-Acetylcysteine effects on glutathione and glutamate in schizophrenia: A preliminary MRS study
  • Oral N-acetylcysteine reduces plasma homocysteine concentrations regardless of lipid or smoking status.
  • N‐acetylcysteine prevents glutathione decrease and does not interfere with paracetamol antinociceptive effect at therapeutic dosage: a randomized double‐blind controlled trial in healthy subjects
  • Meta-analysis of randomised controlled trials with N-acetylcysteine in the treatment of schizophrenia
  • N‐acetylcysteine for depression and glutamate changes in the left prefrontal cortex in adolescents and young adults at risk for bipolar disorder: A pilot study
  • N-acetyl cysteine in the treatment of cannabis use disorder: A systematic review of clinical trials.
  • A double-blind randomized controlled trial of N-acetylcysteine in cannabis-dependent adolescents.
  • N-acetylcysteine for the prevention of contrast-induced nephropathy in patients with pre-existing renal insufficiency or diabetes: a systematic review and meta-analysis
  • A double-blinded, placebo-controlled, multicenter clinical trial of N-acetylcysteine for preventing amphotericin B-induced nephrotoxicity
  • A systematic review and meta-analysis of the efficacy and safety of N-acetylcysteine in preventing aminoglycoside-induced ototoxicity: implications for the treatment of multidrug-resistant TB
  • Protective effects of vitamins/antioxidants on occupational noise‐induced hearing loss: A systematic review
  • Efficacy and safety of N-acetylcysteine in prevention of noise induced hearing loss: A randomized clinical trial

• Leucine

  150 mg

  Ingredient research · Leucine

  Leucine is an essential branched-chain amino acid that serves as a key signal for muscle protein synthesis, helping explain its use around resistance training and in older adults. Supplementation may support muscle maintenance or growth when dietary protein is insufficient, but it cannot replace the full range of amino acids supplied by complete protein.

  • Supports muscle protein synthesis in older adults at rest and around resistance exercise.
  • Supports strength gains in initially untrained men during supervised resistance training.

  Top References

  • Leucine supplementation enhances integrative myofibrillar protein synthesis in free-living older men consuming lower- and higher-protein diets: a parallel-group crossover study.
  • The effectiveness of leucine on muscle protein synthesis, lean body mass and leg lean mass accretion in older people: a systematic review and meta-analysis.
  • Daily L-leucine supplementation in novice trainees during a 12-week weight training program.

• Mixed Tocopherols(High-Gamma Mixed Tocopherols (Form: as d-gamma {tocopherol}, d-delta {tocopherol}, d-alpha {tocopherol}, d-beta {tocopherol}))

  105 mg

  Ingredient research · Tocopherols

  Tocopherols are a family of fat-soluble vitamin E compounds that help protect cell membranes from oxidative damage; alpha-tocopherol is the form the body preferentially retains and uses to meet vitamin E needs. Supplements can prevent or correct deficiency, while claimed advantages of mixed tocopherols for broader cardiovascular or immune benefits remain uncertain.

• Alpha Lipoic Acid

  90 mg

  Ingredient research · Alpha-Lipoic Acid

  Alpha-Lipoic Acid is a sulfur-containing compound that helps mitochondrial enzymes turn nutrients into energy and can also regenerate antioxidants. As a supplement, it may ease pain, burning, or numbness from diabetic peripheral neuropathy, while proposed benefits for blood sugar control and other oxidative-stress-related conditions are less certain.

  • Supports selected glucose, HbA1c, and fasting-insulin markers, especially in adults with metabolic conditions.
  • Supports total-cholesterol, LDL-cholesterol, and triglyceride markers in adults.
  • Supports body-weight, body-mass-index, and waist-circumference measures in adults.
  • Supports endothelial-function and blood-flow measures in adults with vascular or metabolic risk.
  • Supports selected peripheral-neuropathy symptoms in adults receiving paclitaxel or living with diabetic neuropathy.

  Top References

  • The effects of alpha-lipoic acid supplementation on glucose control and lipid profiles among patients with metabolic diseases: A systematic review and meta-analysis of randomized controlled trials.
  • An updated systematic review and dose-response meta-analysis of the effects of α-lipoic acid supplementation on glycemic markers in adults.
  • Alpha-lipoic acid (ALA) supplementation effect on glycemic and inflammatory biomarkers: A Systematic Review and meta- analysis.
  • Effect of alpha-lipoic acid supplementation on lipid profile: A systematic review and meta-analysis of controlled clinical trials.
  • Alpha-lipoic acid supplement in obesity treatment: A systematic review and meta-analysis of clinical trials.
  • Role of alpha-lipoic acid in vascular function: A systematic review of human intervention studies
  • Role of alpha-lipoic acid in counteracting paclitaxel- and doxorubicin-induced toxicities: a randomized controlled trial in breast cancer patients
  • Therapeutic effects of dietary antioxidative supplements on the management of type 2 diabetes and its complications; umbrella review of observational/trials meta-analysis studies

• Green Tea Extract(Green Tea Extract (Form: standardized to contain 98% polyphenols, and 45% EGCg) PlantPart: leaf Genus: Camellia Species: sinensis)

  50 mg

  Ingredient research · Green Tea Extract

  Green Tea Extract concentrates tea catechins, especially EGCG, and often contains caffeine. It may offer modest support for weight management and cardiometabolic health, but effects are generally small and product-dependent; unlike brewed tea, concentrated extracts can rarely cause liver injury, making formulation and use context especially relevant.

  • Supports selected metabolic and liver markers in adults with non-alcoholic fatty liver disease.
  • Supports ambulatory blood-pressure measures in obese women with prehypertension.

  Top References

  • Therapeutic benefits of green tea extract on various parameters in non-alcoholic fatty liver disease patients
  • Short-term Effects of Green Tea on Blood Pressure, Endothelial Function, and Metabolic Profile in Obese Prehypertensive Women: A Crossover Randomized Clinical Trial

• Turmeric(Turmeric (Form: standardized to contain 95% Curcuminoids) PlantPart: root Genus: Curcuma Species: longa)

  50 mg

  Ingredient research · Turmeric

  Turmeric is a botanical whose curcuminoids and other compounds motivate its use for anti-inflammatory effects. Supplements, particularly standardized extracts, may modestly ease osteoarthritis-related joint pain, but whole-turmeric products are not interchangeable with isolated curcumin, and proposed digestive or metabolic benefits are less certain.

• Grape Seed Extract(Grape Seed Extract (Form: standardized to contain 95% oligomeric proanthocyanidins (Form: complexed with phosphatidylcholine)) (Alt. Name: Leucoselect(R) Phytosome(TM)) PlantPart: seed Genus: Vitis Species: vinifera)

  50 mg

  Ingredient research · Grape Seed Extract

  Grape Seed Extract is a concentrated source of proanthocyanidins, polyphenols that influence antioxidant defenses and blood-vessel function. Supplementation may modestly support circulation and healthy blood pressure, with possible relevance to swelling and skin health; it is distinct from resveratrol-rich grape products and their associated claims.

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