ProSoothe II

Ingredient research · Vitamin D

Vitamin D is a hormone-like nutrient that helps the body absorb calcium and maintain healthy bones and muscle function. Supplementation can reliably prevent or correct low vitamin D status, particularly when sun exposure is limited, while broader immune, cardiovascular, and metabolic benefits are less certain.

• Supports bone-density and fracture- or fall-related outcomes.
• Supports muscle-strength outcomes, including lower-limb strength.
• Supports glycemic-marker and insulin-sensitivity outcomes in studied metabolic populations.
• Supports respiratory-infection-risk outcomes across studied age groups.

Ingredient research · Vitamin E

Vitamin E is an essential fat-soluble antioxidant that protects cell membranes from oxidative damage and supports normal immune and nerve function. Supplementation is most useful for preventing or correcting deficiency, particularly when fat absorption is impaired; routine use has not shown broad protection against cardiovascular disease or cancer.

• Supports improvement in liver histology in adults without diabetes who have biopsy-confirmed nonalcoholic steatohepatitis.
• Supports lower CRP and malondialdehyde in studied adult populations, including people receiving hemodialysis.
• Supports short-term improvements in fasting glucose and HbA1c in adults with type 2 diabetes.

Ingredient research · Vitamin B6

Vitamin B6 is an essential nutrient that helps enzymes process amino acids and supports neurotransmitter, hemoglobin, and immune function. Supplementation reliably corrects deficiency and can reduce nausea during pregnancy; outside these uses, it is most relevant when intake or absorption is inadequate.

• Supports depressive-symptom measures in premenopausal women with hormone-related contexts.

Ingredient research · Calcium

Calcium is an essential mineral that gives bones and teeth their structure and also enables muscle contraction and nerve signaling. Supplements are most useful for filling inadequate intake and, often alongside vitamin D, can help preserve bone mineral density and support fracture prevention in some higher-risk groups.

• Supports bone-mineral-density outcomes in studied healthy children and older women.

Ingredient research · Magnesium

Magnesium is an essential mineral that enables normal muscle and nerve function, energy production, heart rhythm, and bone maintenance. Supplements can correct low magnesium status and, depending on the formulation, may also help with constipation, muscle cramps, or migraine prevention in some people.

Ingredient research · Chasteberry

Chasteberry is a botanical preparation from the Vitex shrub, used mainly for menstrual-cycle symptoms—particularly the mood changes, irritability, and breast tenderness associated with premenstrual syndrome. Its compounds may influence dopamine and prolactin signaling, while benefits for fertility or menopausal symptoms are less clearly established.

Ingredient research · Rhodiola rosea root extract

Rhodiola rosea root extract is a botanical “adaptogen” used to make physical and mental strain feel more manageable. It may modestly reduce fatigue, stress-related exhaustion, or perceived effort during demanding periods, but effects depend on the extract, and distinct benefits for mood, cognition, and exercise performance remain uncertain.