Amino-NR

Ingredient research · Vitamin B6

Vitamin B6 is an essential nutrient that helps enzymes process amino acids and supports neurotransmitter, hemoglobin, and immune function. Supplementation reliably corrects deficiency and can reduce nausea during pregnancy; outside these uses, it is most relevant when intake or absorption is inadequate.

• Supports depressive-symptom measures in premenopausal women with hormone-related contexts.

Ingredient research · Vitamin B12

Vitamin B12 is an essential nutrient needed for red blood cell formation, DNA synthesis, and normal nerve function. Supplementation reliably prevents or corrects deficiency—especially when intake or absorption is limited—and may improve anemia, fatigue, or neurologic symptoms caused by low B12, but is not a general energy booster when status is adequate.

• Supports vitamin B12 status and responsive deficiency markers in low-status populations, including maternal and breast-milk status during pregnancy and early lactation.

Ingredient research · Alpha-Lipoic Acid

Alpha-Lipoic Acid is a sulfur-containing compound that helps mitochondrial enzymes turn nutrients into energy and can also regenerate antioxidants. As a supplement, it may ease pain, burning, or numbness from diabetic peripheral neuropathy, while proposed benefits for blood sugar control and other oxidative-stress-related conditions are less certain.

• Supports selected glucose, HbA1c, and fasting-insulin markers, especially in adults with metabolic conditions.
• Supports total-cholesterol, LDL-cholesterol, and triglyceride markers in adults.
• Supports body-weight, body-mass-index, and waist-circumference measures in adults.
• Supports endothelial-function and blood-flow measures in adults with vascular or metabolic risk.
• Supports selected peripheral-neuropathy symptoms in adults receiving paclitaxel or living with diabetic neuropathy.

Ingredient research · L-Histidine

L-Histidine is an essential amino acid needed for protein synthesis and for making histamine and carnosine, molecules involved in immune and digestive signaling and muscle buffering. Supplementation is most relevant when dietary intake or increased needs are not met; distinct benefits for exercise, fatigue, or other conditions remain uncertain.

• Supports the HOMA-IR insulin-resistance marker in women with obesity and metabolic syndrome.
• Supports selected body measurements and fat-mass outcomes in women with obesity and metabolic syndrome.
• Supports selected inflammatory-marker outcomes in women with obesity and metabolic syndrome.

Ingredient research · L-Isoleucine

L-Isoleucine is an essential branched-chain amino acid used to build proteins and as fuel by muscle and other tissues. Supplements are mainly intended to bolster amino acid availability around exercise or when protein intake is limited, but isolated isoleucine has no clear advantage over adequate complete protein or balanced essential amino acids.

Ingredient research · Leucine

Leucine is an essential branched-chain amino acid that serves as a key signal for muscle protein synthesis, helping explain its use around resistance training and in older adults. Supplementation may support muscle maintenance or growth when dietary protein is insufficient, but it cannot replace the full range of amino acids supplied by complete protein.

• Supports muscle protein synthesis in older adults at rest and around resistance exercise.
• Supports strength gains in initially untrained men during supervised resistance training.

Ingredient research · L-Methionine

L-Methionine is an essential amino acid used to build proteins and produce SAMe, cysteine, and glutathione. Supplementation is mainly relevant when dietary intake or absorption is inadequate or in specialized clinical nutrition; extra methionine has no broadly established benefit for well-nourished people and can raise homocysteine.

Ingredient research · L-Phenylalanine

L-Phenylalanine is an essential amino acid used to build proteins and make tyrosine, which in turn contributes to dopamine, norepinephrine, thyroid hormones, and melanin. Supplements are often considered for mood or focus, but distinct benefits beyond meeting nutritional needs are uncertain; people with phenylketonuria must restrict phenylalanine.

• Supports acute satiety and reduced food intake under controlled feeding conditions.
• Supports the acute postprandial blood-glucose response in controlled feeding studies.

Ingredient research · L-Threonine

L-Threonine is an essential amino acid needed to build proteins and produce mucins that help maintain the intestinal barrier. Supplementation can help meet threonine needs when dietary protein or amino acid intake is inadequate, but isolated supplementation has no clearly established added benefit for most well-nourished people.

Ingredient research · Valine

Valine is an essential branched-chain amino acid needed for protein synthesis and also used by muscles as fuel during exercise. Supplements are usually intended to support muscle maintenance or recovery, but isolated valine has little established advantage when overall protein and essential amino acid intake is already adequate.

Ingredient research · L-Alanine

L-Alanine is a nonessential amino acid used to build proteins and shuttle nitrogen and carbon between muscle and liver during energy metabolism. Although included in some sports and amino acid formulas, it is rarely needed on its own, and distinct benefits from alanine supplementation remain poorly established.

Ingredient research · L-Arginine hydrochloride

L-Arginine hydrochloride is a soluble salt of arginine, an amino acid used to make nitric oxide, which relaxes blood vessels. Supplementation may improve blood flow and modestly benefit blood pressure or erectile function in some settings, but the hydrochloride form has no established advantage beyond formulation properties.

• Supports selected weight-status and C-reactive-protein measures during treatment for active tuberculosis.
• Supports selected perioperative redox markers when added to cardioplegia during coronary bypass surgery.

Ingredient research · L-Glutamine

L-Glutamine is a conditionally essential amino acid that transports nitrogen and fuels cells in the intestine and immune system. The body usually makes enough, but demand can rise during major illness or injury; a prescription oral formulation can reduce sickle cell disease complications, while routine benefits for exercise recovery or gut health are less certain.

• Supports selected intestinal-barrier, absorption, and bowel-function measures in postinfectious IBS-D and during fluorouracil chemotherapy.
• Supports selected glycemic and incretin markers, including glucose-related measures and GLP-1, in diabetes or older-adult metabolic contexts.

Ingredient research · Glycine

Glycine is a simple amino acid used to build proteins—especially collagen—and to make glutathione and other important molecules; it also acts as an inhibitory neurotransmitter. Supplementation may modestly improve sleep quality and next-day alertness, while proposed metabolic and connective-tissue benefits are less certain.

Ingredient research · L-Proline

L-Proline is an amino acid the body uses extensively to build collagen, giving it a clear structural role in skin, tendons, cartilage, and wound repair. Supplements are therefore taken for connective-tissue and exercise-recovery support, but distinct benefits from extra proline in otherwise well-nourished people remain uncertain.

Ingredient research · L-Serine

L-Serine is a naturally occurring amino acid used to build proteins and important membrane lipids, while also contributing to several signaling molecules. Supplementation can address low serine in rare inherited synthesis disorders and is being explored for broader brain and nerve health, though benefits for generally healthy people remain uncertain.

Ingredient research · L-Tyrosine

L-Tyrosine is an amino acid the body uses to make dopamine, norepinephrine, and thyroid hormones. Supplementation may help preserve attention, working memory, and mental performance during acute stressors such as sleep loss or cold exposure, but it is not a reliably effective everyday cognitive or mood enhancer.

• Supports cycling endurance during exercise in the heat.

Ingredient research · L-Tryptophan

L-Tryptophan is an essential amino acid used to make proteins and the signaling molecules serotonin and melatonin. As a supplement, it may support sleep and mood by increasing precursor availability, though these effects are context-dependent; it also contributes to niacin production when dietary niacin is limited.

• Supports sleep continuity by reducing wakefulness after sleep onset.

Ingredient research · Taurine

Taurine is a sulfur-containing amino acid-like compound that helps regulate cell hydration, bile acid formation, and normal nerve and muscle function; unlike caffeine, it is not a stimulant. Supplementation may modestly support exercise performance and recovery, with possible relevance to cardiovascular and metabolic health.

• Supports blood-pressure control.