Research paper
Taurine Supplementation Lowers Blood Pressure and Improves Vascular Function in Prehypertension: Randomized, Double-Blind, Placebo-Controlled Study
Study answer
What this study found
Taurine supplementation lowered blood pressure and improved vascular function over 12 weeks. In the taurine group, clinic SBP fell from 130.0±5.64 to 122.8±10.57 and clinic DBP from 77.7±6.87 to 73.1±8.66; 24-hour SBP fell from 119.4±9.37 to 115.6±8.35 and 24-hour DBP from 76.0±7.97 to 72.5±8.22. Daytime ambulatory SBP and DBP also decreased, endothelial-dependent vasodilation increased by 3.2%, and endothelial-independent vasodilation increased by 4.4%. Plasma H2S increased from 43.8±20.82 to 87.0±24.51 µmol/L and plasma taurine from 108.3±55.27 to 142.3±62.14 µmol/L, with BP changes…
- Study & population
- Single-center, randomized, double-blind, placebo-controlled trial in adults with prehypertension in Chongqing, China.
- Intervention
- Oral taurine (2-aminoethanesulfonic acid) was given at 1.6 g/day once daily between 08:00 and 09:00 am for 12 weeks.
- Key limitation
- The trial was single-center, relatively small, and short in duration, limiting durability and generalizability.
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Open PDFOriginal abstract
Taurine, the most abundant, semiessential, sulfur-containing amino acid, is well known to lower blood pressure (BP) in hypertensive animal models. However, no rigorous clinical trial has validated whether this beneficial effect of taurine occurs in h…