Thyrotain
Price
Retail
$45.40
Container
30 servings
Serving
4 Capsules
Brand Quality
Why this score
Testing practices
- Lot Tested
- Third-Party Lab Tested
- Transparent Batch-Specific COAs
- ISO 17025 Lab
Testing coverage
- Identity
- Purity
- Potency
- Heavy Metals
- Raw Ingredient Testing
Certifications
- NSF Certified
Manufacturing standards
- cGMP Certified
- Made in USA
Innovation
- Clinically Studied Product
Active Ingredients
- 750 mcg
Vitamin A(2,500 IU Vitamin A Palmitate)
Ingredient research · Vitamin A
Vitamin A is an essential fat-soluble nutrient that enables normal vision, especially in dim light, and helps maintain immune defenses, skin and other epithelial tissues, growth, and reproduction. Supplementation can prevent or correct deficiency when intake or absorption is inadequate, benefiting visual, immune, and developmental health.
- Supports maternal and breast-milk vitamin A status, particularly where baseline stores are low.
- Supports hemoglobin response in some anemic or vitamin A-deficient populations, including when added to iron and folate.
- Supports reducing bacterial-vaginosis incidence and prevalence during pregnancy and postpartum follow-up in a studied deficient setting.
Top References
- Efect of vitamin A suplementation: a systematic review.
- Retinol-to-Fat Ratio and Retinol Concentration in Human Milk Show Similar Time Trends and Associations with Maternal Factors at the Population Level: A Systematic Review and Meta-Analysis.
- Vitamin A supplementation for postpartum women.
- Concomitant supplemental vitamin A enhances the response to weekly supplemental iron and folic acid in anemic teenagers in urban Bangladesh.
- Weekly supplementation with iron and vitamin A during pregnancy increases hemoglobin concentration but decreases serum ferritin concentration in Indonesian pregnant women.
- Maternal vitamin A and β-carotene supplementation and risk of bacterial vaginosis: a randomized controlled trial in rural Bangladesh.
- 200 mg
Vitamin C(USP)
Ingredient research · Vitamin C
Vitamin C is an essential water-soluble nutrient that supports collagen production, antioxidant defenses, and the normal function of immune cells. Supplementation reliably prevents or corrects deficiency, can improve absorption of plant-based iron, and may modestly shorten the duration of common colds when taken regularly.
- Supports lower common-cold risk during brief periods of severe physical exercise or cold stress.
- Supports circulating Vitamin C status across studied healthy and clinical populations.
- Supports short-term blood-pressure and endothelial-function outcomes in studied adults.
- Supports fasting-glucose and HbA1c outcomes in adults with type 2 diabetes.
Top References
- Vitamin C for preventing and treating the common cold.
- Effect of Dietary or Supplemental Vitamin C Intake on Vitamin C Levels in Patients with and without Cardiovascular Disease: A Systematic Review
- High-dose vitamin C supplementation increases skeletal muscle vitamin C concentration and SVCT2 transporter expression but does not alter redox status in healthy males.
- Effects of vitamin C supplementation on blood pressure: a meta-analysis of randomized controlled trials.
- Effect of vitamin C and vitamin E supplementation on endothelial function: a systematic review and meta-analysis of randomised controlled trials
- Effects of vitamin C supplementation on glycaemic control: a systematic review and meta-analysis of randomised controlled trials
- Effect of vitamin C on inflammation and metabolic markers in hypertensive and/or diabetic obese adults: a randomized controlled trial
- Supplementation of Vitamin C Reduces Blood Glucose and Improves Glycosylated Hemoglobin in Type 2 Diabetes Mellitus: A Randomized, Double-Blind Study
- 134 mg
Vitamin E(200 IU, USP)
Ingredient research · Vitamin E
Vitamin E is an essential fat-soluble antioxidant that protects cell membranes from oxidative damage and supports normal immune and nerve function. Supplementation is most useful for preventing or correcting deficiency, particularly when fat absorption is impaired; routine use has not shown broad protection against cardiovascular disease or cancer.
- Supports improvement in liver histology in adults without diabetes who have biopsy-confirmed nonalcoholic steatohepatitis.
- Supports lower CRP and malondialdehyde in studied adult populations, including people receiving hemodialysis.
- Supports short-term improvements in fasting glucose and HbA1c in adults with type 2 diabetes.
Top References
- Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis.
- The effect of vitamin E supplementation on selected inflammatory biomarkers in adults: a systematic review and meta-analysis of randomized clinical trials
- The effects of vitamin E supplementation on malondialdehyde as a biomarker of oxidative stress in haemodialysis patients: a systematic review and meta-analysis
- Effect of supplementation with tomato juice, vitamin E, and vitamin C on LDL oxidation and products of inflammatory activity in type 2 diabetes.
- Antioxidant effects of vitamins in type 2 diabetes: a meta-analysis of randomized controlled trials
- 200 mcg
Iodine
Ingredient research · Iodine
Iodine is an essential mineral the thyroid uses to make hormones that regulate metabolism, growth, and development. Supplementation reliably prevents or corrects iodine deficiency and is especially important when needs rise during pregnancy for fetal brain development, but excess intake can also disturb thyroid function.
- Supports selected micronutrient and thyroid-status markers in iodine-deficient adults.
- 20 mg
Zinc
Ingredient research · Zinc
Zinc is an essential mineral needed for hundreds of enzymes, DNA and protein synthesis, immune defense, wound healing, and normal growth. Supplementation corrects low zinc status and helps restore these functions; certain zinc lozenges may also modestly shorten a common cold when used early, though this benefit depends on the formulation.
- 200 mcg
Selenium
Ingredient research · Selenium
Selenium is an essential trace mineral used to make antioxidant enzymes and regulate thyroid hormone activity, linking adequate intake to thyroid, immune, and reproductive function. Supplementation can correct low selenium status, but more is not necessarily better because excessive intake can be toxic.
- Supports selected thyroid-autoantibody and TSH markers in studied people with autoimmune thyroiditis.
- Supports selected antioxidant-defense biomarkers in studied metabolic, cardiovascular, and selenium-status populations.
- Supports depression-symptom measures across a small selenium-specific randomized evidence base.
Top References
- Selenium Supplementation Significantly Reduces Thyroid Autoantibody Levels in Patients with Chronic Autoimmune Thyroiditis: A Systematic Review and Meta-Analysis.
- Effect of selenium on thyroid autoimmunity and regulatory T cells in patients with Hashimoto’s thyroiditis: A prospective randomized‐controlled trial
- Effect of selenium supplementation on antioxidant markers: a systematic review and meta-analysis of randomized controlled trials
- The effect of selenium supplementation on coronary heart disease: A systematic review and meta-analysis of randomized controlled trials.
- Methods of assessment of selenium status in humans: a systematic review.
- The role of selenium in depression: a systematic review and meta-analysis of human observational and interventional studies
- 500 mg
N-Acetyl-L-Cysteine(USP)
Ingredient research · NAC
NAC is a cysteine derivative that helps replenish glutathione, a major cellular antioxidant, and also thins mucus by breaking bonds in its proteins. As a supplement, it may support antioxidant defenses and respiratory health; acetylcysteine also has established medical uses as a mucolytic and as an antidote for acetaminophen poisoning.
- Supports glutathione and antioxidant-defense measures.
- Supports depressive symptoms and negative symptoms of schizophrenia.
- Supports cannabis-use, craving, and abstinence outcomes.
- Evidence supports kidney-function and injury-marker outcomes in clinical treatment settings.
- Supports hearing-loss and ototoxicity outcomes in noise- and medication-exposure settings.
Top References
- N-Acetylcysteine effects on glutathione and glutamate in schizophrenia: A preliminary MRS study
- Oral N-acetylcysteine reduces plasma homocysteine concentrations regardless of lipid or smoking status.
- N‐acetylcysteine prevents glutathione decrease and does not interfere with paracetamol antinociceptive effect at therapeutic dosage: a randomized double‐blind controlled trial in healthy subjects
- Meta-analysis of randomised controlled trials with N-acetylcysteine in the treatment of schizophrenia
- N‐acetylcysteine for depression and glutamate changes in the left prefrontal cortex in adolescents and young adults at risk for bipolar disorder: A pilot study
- N-acetyl cysteine in the treatment of cannabis use disorder: A systematic review of clinical trials.
- A double-blind randomized controlled trial of N-acetylcysteine in cannabis-dependent adolescents.
- N-acetylcysteine for the prevention of contrast-induced nephropathy in patients with pre-existing renal insufficiency or diabetes: a systematic review and meta-analysis
- A double-blinded, placebo-controlled, multicenter clinical trial of N-acetylcysteine for preventing amphotericin B-induced nephrotoxicity
- A systematic review and meta-analysis of the efficacy and safety of N-acetylcysteine in preventing aminoglycoside-induced ototoxicity: implications for the treatment of multidrug-resistant TB
- Protective effects of vitamins/antioxidants on occupational noise‐induced hearing loss: A systematic review
- Efficacy and safety of N-acetylcysteine in prevention of noise induced hearing loss: A randomized clinical trial
- 400 mg
L-Tyrosine(USP)
Ingredient research · L-Tyrosine
L-Tyrosine is an amino acid the body uses to make dopamine, norepinephrine, and thyroid hormones. Supplementation may help preserve attention, working memory, and mental performance during acute stressors such as sleep loss or cold exposure, but it is not a reliably effective everyday cognitive or mood enhancer.
- Supports cycling endurance during exercise in the heat.
- 300 mg
Ashwagandha root extract(standardized to 1.5% Withanolides)
Ingredient research · Ashwagandha Root Powder Extract
Ashwagandha Root Powder Extract is a concentrated preparation of the plant’s root, traditionally used to improve resilience to stress. It may modestly reduce perceived stress and anxiety and improve sleep, while possible benefits for exercise performance and male reproductive health are less consistent; effects can depend on extraction and standardization.
- 150 mg
Guggul
Ingredient research · Guggul
Guggul is a resin from the Commiphora wightii tree used in Ayurvedic medicine; its extracts contain guggulsterones, compounds proposed to affect lipid metabolism and inflammatory signaling. It is supplemented mainly for cholesterol and triglyceride control, with additional interest in weight and joint health, but consistent human benefits have not been demonstrated.
- 100 mg
Turmeric Root Extract(45-55% Curcuminoids, 3-8% Volatile Oil, 2-6% Turmerin)
Ingredient research · Turmeric
Turmeric is a botanical whose curcuminoids and other compounds motivate its use for anti-inflammatory effects. Supplements, particularly standardized extracts, may modestly ease osteoarthritis-related joint pain, but whole-turmeric products are not interchangeable with isolated curcumin, and proposed digestive or metabolic benefits are less certain.
Inactive Ingredients
9.2 Safe
- natural Vegetable CapsulesIdeal
- Microcrystalline CelluloseIdeal
- Magnesium StearateSafe
- Calcium SilicateSafe
- Silicon DioxideIdeal
These statements have not been evaluated by the Food and Drug Administration. Any products and informational content displayed on this page are not intended to diagnose, treat, cure, or prevent any disease.