CardioMAX

• Red Yeast Rice(Liposomal)

  400 mg

  Ingredient research · Red Yeast Rice

  Red Yeast Rice is fermented rice that may contain monacolin K, the same active compound as the prescription statin lovastatin. Products with meaningful amounts can lower LDL cholesterol, but monacolin content varies widely, and their potential muscle, liver, pregnancy, and drug-interaction concerns resemble those of statins.

  • Supports LDL, total cholesterol, and triglyceride markers.

  Top References

  • Cholesterol-lowering effects of a proprietary Chinese red-yeast-rice dietary supplement.
  • Impact of red yeast rice supplementation on lipid profile: a systematic review and meta-analysis of randomized-controlled trials

• Niacin(Liposomal)

  125 mg

  Ingredient research · Niacin

  Niacin is vitamin B3, essential for enzymes that convert food into energy and support normal skin and nervous-system function. Supplementation prevents or corrects deficiency; in high-dose nicotinic acid form it can alter cholesterol and triglycerides, but this pharmacologic use is distinct from routine nutritional supplementation.

  • Supports favorable changes in selected cholesterol fractions, including LDL, HDL, and total cholesterol, in studied metabolic and diabetes populations.
  • Supports favorable fasting-triglyceride changes in studied adults with diabetes or metabolic dysregulation.

  Top References

  • Effectiveness of niacin supplementation for patients with type 2 diabetes
  • Effect of niacin on lipids and glucose in patients with type 2 diabetes: A meta-analysis of randomized, controlled clinical trials.
  • Niacin induces miR-502-3p expression which impairs insulin sensitivity in human adipocytes
  • Postprandial triglyceride responses to aerobic exercise and extended-release niacin.

• Coenzyme Q-10(Liposomal)

  100 mg

  Ingredient research · CoQ10

  CoQ10 is a vitamin-like compound that helps mitochondria make cellular energy and also acts as an antioxidant. Supplements can modestly improve symptoms and exercise capacity in some people with heart failure, and may help prevent migraines or ease statin-associated muscle symptoms, though these uses are less consistent.

  • Supports fatigue-related symptom outcomes.
  • Supports migraine frequency, duration, and severity outcomes.
  • Supports blood-glucose and insulin-related markers.
  • Supports heart-failure functional-class and hospitalization outcomes.
  • Supports sperm count, motility, morphology, and fertility-related outcomes.

  Top References

  • Effectiveness of Coenzyme Q10 Supplementation for Reducing Fatigue: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
  • Coenzyme Q10 supplementation reduces peripheral oxidative stress and inflammation in interferon-β1a-treated multiple sclerosis
  • Oral coenzyme Q10 supplementation in patients with migraine: Effects on clinical features and inflammatory markers
  • Effectiveness of coenzyme Q10 in prophylactic treatment of migraine headache: an open-label, add-on, controlled trial
  • Effectiveness of Coenzyme Q10 Supplementation for Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis
  • Hormonal and Metabolic Effects of Coenzyme Q10 and/or Vitamin E in Patients With Polycystic Ovary Syndrome
  • Coenzyme Q10 for heart failure.
  • Effect of coenzyme Q10 therapy in patients with congestive heart failure: a long-term multicenter randomized study
  • Randomised double-blind, placebo-controlled trial of coenzyme Q10 therapy in class II and III systolic heart failure
  • Nutritional modifications in male infertility: a systematic review covering 2 decades.
  • The effect of coenzyme Q10 supplementation on partner pregnancy rate in infertile men with idiopathic oligoasthenoteratozoospermia: an open-label prospective study

• Berberine(Liposomal)

  100 mg

  Ingredient research · Berberine

  Berberine is a plant-derived alkaloid that influences cellular energy sensing and gut-related metabolism. As a supplement, it can modestly improve blood sugar control and blood lipid levels, particularly in people with metabolic disorders, while its effects on weight and other proposed uses are less consistent.

  • Supports blood-glucose, HbA1c, and insulin-resistance markers.
  • Supports LDL, total-cholesterol, and triglyceride markers.
  • Supports body-weight, BMI, and waist-circumference measures.
  • Supports liver-fat and selected liver-enzyme measures in nonalcoholic fatty liver disease.

  Top References

  • Efficacy of Berberine in Patients with Non-Alcoholic Fatty Liver Disease
  • The Therapeutic Effect of Berberine in the Treatment of Nonalcoholic Fatty Liver Disease: A Meta-Analysis
  • The clinical efficacy and safety of berberine in the treatment of non-alcoholic fatty liver disease: a meta-analysis and systematic review
  • Efficacy and Safety of Berberine Alone or Combined with Statins for the Treatment of Hyperlipidemia: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials.
  • The effect of berberine supplementation on obesity parameters, inflammation and liver function enzymes: A systematic review and meta-analysis of randomized controlled trials.

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