Dry E-400 IU Plus Selenium

• Vitamin E(Vitamin E (Form: as D-Alpha Tocopheryl Succinate))

  400 IU

  Ingredient research · Vitamin E

  Vitamin E is an essential fat-soluble antioxidant that protects cell membranes from oxidative damage and supports normal immune and nerve function. Supplementation is most useful for preventing or correcting deficiency, particularly when fat absorption is impaired; routine use has not shown broad protection against cardiovascular disease or cancer.

  • Supports improvement in liver histology in adults without diabetes who have biopsy-confirmed nonalcoholic steatohepatitis.
  • Supports lower CRP and malondialdehyde in studied adult populations, including people receiving hemodialysis.
  • Supports short-term improvements in fasting glucose and HbA1c in adults with type 2 diabetes.

  Top References

  • Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis.
  • The effect of vitamin E supplementation on selected inflammatory biomarkers in adults: a systematic review and meta-analysis of randomized clinical trials
  • The effects of vitamin E supplementation on malondialdehyde as a biomarker of oxidative stress in haemodialysis patients: a systematic review and meta-analysis
  • Effect of supplementation with tomato juice, vitamin E, and vitamin C on LDL oxidation and products of inflammatory activity in type 2 diabetes.
  • Antioxidant effects of vitamins in type 2 diabetes: a meta-analysis of randomized controlled trials

• Selenium(Selenium (Form: as yeast-free L-Selenomethionine))

  200 mcg

  Ingredient research · Selenium

  Selenium is an essential trace mineral used to make antioxidant enzymes and regulate thyroid hormone activity, linking adequate intake to thyroid, immune, and reproductive function. Supplementation can correct low selenium status, but more is not necessarily better because excessive intake can be toxic.

  • Supports selected thyroid-autoantibody and TSH markers in studied people with autoimmune thyroiditis.
  • Supports selected antioxidant-defense biomarkers in studied metabolic, cardiovascular, and selenium-status populations.
  • Supports depression-symptom measures across a small selenium-specific randomized evidence base.

  Top References

  • Selenium Supplementation Significantly Reduces Thyroid Autoantibody Levels in Patients with Chronic Autoimmune Thyroiditis: A Systematic Review and Meta-Analysis.
  • Effect of selenium on thyroid autoimmunity and regulatory T cells in patients with Hashimoto’s thyroiditis: A prospective randomized‐controlled trial
  • Effect of selenium supplementation on antioxidant markers: a systematic review and meta-analysis of randomized controlled trials
  • The effect of selenium supplementation on coronary heart disease: A systematic review and meta-analysis of randomized controlled trials.
  • Methods of assessment of selenium status in humans: a systematic review.
  • The role of selenium in depression: a systematic review and meta-analysis of human observational and interventional studies

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