Buffered Vitamin C-500 mg

• Vitamin C(Vitamin C (Form: as Calcium Ascorbate))

  500 mg

  Ingredient research · Vitamin C

  Vitamin C is an essential water-soluble nutrient that supports collagen production, antioxidant defenses, and the normal function of immune cells. Supplementation reliably prevents or corrects deficiency, can improve absorption of plant-based iron, and may modestly shorten the duration of common colds when taken regularly.

  • Supports lower common-cold risk during brief periods of severe physical exercise or cold stress.
  • Supports circulating Vitamin C status across studied healthy and clinical populations.
  • Supports short-term blood-pressure and endothelial-function outcomes in studied adults.
  • Supports fasting-glucose and HbA1c outcomes in adults with type 2 diabetes.

  Top References

  • Vitamin C for preventing and treating the common cold.
  • Effect of Dietary or Supplemental Vitamin C Intake on Vitamin C Levels in Patients with and without Cardiovascular Disease: A Systematic Review
  • High-dose vitamin C supplementation increases skeletal muscle vitamin C concentration and SVCT2 transporter expression but does not alter redox status in healthy males.
  • Effects of vitamin C supplementation on blood pressure: a meta-analysis of randomized controlled trials.
  • Effect of vitamin C and vitamin E supplementation on endothelial function: a systematic review and meta-analysis of randomised controlled trials
  • Effects of vitamin C supplementation on glycaemic control: a systematic review and meta-analysis of randomised controlled trials
  • Effect of vitamin C on inflammation and metabolic markers in hypertensive and/or diabetic obese adults: a randomized controlled trial
  • Supplementation of Vitamin C Reduces Blood Glucose and Improves Glycosylated Hemoglobin in Type 2 Diabetes Mellitus: A Randomized, Double-Blind Study

• Calcium(Calcium (Form: as Calcium Ascorbate))

  56 mg

  Ingredient research · Calcium

  Calcium is an essential mineral that gives bones and teeth their structure and also enables muscle contraction and nerve signaling. Supplements are most useful for filling inadequate intake and, often alongside vitamin D, can help preserve bone mineral density and support fracture prevention in some higher-risk groups.

  • Supports bone-mineral-density outcomes in studied healthy children and older women.

  Top References

  • Effects of calcium supplementation on bone density in healthy children: meta-analysis of randomised controlled trials
  • The efficacy of calcium supplementation alone in elderly Thai women over a 2-year period: a randomized controlled trial

• Citrus Bioflavonoids Complex

  250 mg

  Ingredient research · Citrus Bioflavonoids

  Citrus Bioflavonoids are a mixture of citrus-derived plant compounds, often including hesperidin and related flavanones, that can influence antioxidant and blood-vessel signaling. They are mainly supplemented to support capillary and circulatory health or complement vitamin C, but distinct human benefits remain modest and depend on the extract’s composition.

• Hesperidin(Hesperidin (Form: supplying Flavones (Form: Eriocitrin, Naringenin, Narirutin), Flavonols, and other related Phenolic Compounds))

  100 mg

  Ingredient research · Hesperidin

  Hesperidin is a citrus flavonoid whose metabolites may influence blood-vessel function and inflammatory signaling. It is mainly supplemented for circulatory support, including venous symptoms, with possible relevance to cardiovascular and metabolic health; however, many clinical formulations combine it with diosmin, making hesperidin’s independent contribution less clear.

  • Supports liver-fat and liver-enzyme markers in adults with nonalcoholic fatty liver disease.
  • Supports systolic and mean arterial blood-pressure markers in adults with type 2 diabetes.
  • Supports fructosamine and insulin-sensitivity markers in adults with type 2 diabetes or metabolic syndrome.
  • Supports total-cholesterol and triglyceride markers in adults with nonalcoholic fatty liver disease.

  Top References

  • Hesperidin improves hepatic steatosis, hepatic enzymes, and metabolic and inflammatory parameters in patients with nonalcoholic fatty liver disease: A randomized, placebo‐controlled, double‐blind clinical trial
  • Blood pressure lowering and anti‐inflammatory effects of hesperidin in type 2 diabetes; a randomized double‐blind controlled clinical trial
  • Hesperidin Supplementation Alleviates Oxidative DNA Damage and Lipid Peroxidation in Type 2 Diabetes: A Randomized Double‐Blind Placebo‐Controlled Clinical Trial
  • The effect of hesperidin supplementation on metabolic profiles in patients with metabolic syndrome: a randomized, double-blind, placebo-controlled clinical trial

• Rutin

  10 mg

  Ingredient research · Rutin

  Rutin is a plant flavonoid made of quercetin linked to a sugar group, and is taken mainly for its antioxidant activity and proposed support of capillary and venous function. Unlike some modified rutosides, Rutin itself has limited human evidence for circulatory benefits, while broader cardiometabolic or anti-inflammatory uses remain speculative.

Ranking