Skip to content

Research paper

Vitamin D Supplementation and Mental Health in Inflammatory Bowel Diseases and Irritable Bowel Syndrome Patients: A Systematic Review

Nutrients
Q1
Oct 2021
Citations: 15
Influential: 1
Systematic Reviews / Meta-Analyses
84

Study answer

What this study found

The majority of included studies (six studies) demonstrated a positive influence of vitamin D supplementation on mental health, particularly anxiety, depression, and quality of life. Only one study did not support a positive influence.

Study & population
A systematic review included interventions of vitamin D supplementation assessing mental health in adults with IBDs and IBS, involving 10 studies selected from a broader search.
Intervention
Vitamin D supplementation for patients with inflammatory bowel diseases (IBDs) and irritable bowel syndrome (IBS) aimed at improving mental health outcomes.
Key limitation
Limited number of studies, particularly with ulcerative colitis patients and randomized against placebo, and potential overlap in participant data.
View sourceOpen PDF

Original abstract

Inflammatory bowel diseases (IBDs) and irritable bowel syndrome (IBS) are associated with decreased quality of life and mental health problems. Among various approaches to supportive therapy that aims to improve mental health in affected individuals,…