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Research paper

The influence of n-3 polyunsaturated fatty acids on cognitive function in individuals without dementia: a systematic review and dose–response meta-analysis

BMC Medicine
Q1
Mar 2024
Citations: 21
Influential: 1
Systematic Reviews / Meta-Analyses
87

Study answer

What this study found

Background Omega-3 polyunsaturated fatty acids (n-3 PUFA) have been suggested as a cognitive enhancing agent, though their effect is doubtful. We aimed to examine the effect of n-3 PUFA on the cognitive function of middle-aged or older adults without dementia. Methods We reviewed randomized controlled trials of individuals aged 40 years or older. We systematically searched PubMed/MEDLINE, EMBASE, CINAHL, PsycINFO, and Cochrane Library databases. We used the restricted cubic splines model for non-linear dose–response meta-analysis in terms of the standardized mean difference with 95%…

A separate results summary is not available, so this answer uses the paper abstract.

Study & population
Systematic Reviews / Meta-Analyses

Original abstract

Background Omega-3 polyunsaturated fatty acids (n-3 PUFA) have been suggested as a cognitive enhancing agent, though their effect is doubtful. We aimed to examine the effect of n-3 PUFA on the cognitive function of middle-aged or older adults without…