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Research paper

Herbal Medicine for the Treatment of Anorexia in Children: A Systematic Review and Meta-Analysis

Frontiers in Pharmacology
Q1
Apr 2022
Citations: 7
Influential: 0
Systematic Reviews / Meta-Analyses
83

Study answer

What this study found

Overall, herbal medicine improved anorexia outcomes and some appetite- and growth-related measures, especially when used alone or added to active treatment, but the evidence was limited by bias and heterogeneity. Versus placebo, total effective rate was higher (RR 1.58, 95% CI 1.34 to 1.85) and adverse events were not clearly different (RR 0.66, 95% CI 0.25 to 1.75). Versus active control, total effective rate improved (RR 1.25, 95% CI 1.22 to 1.28), with lower recurrence (RR 0.15, 95% CI 0.09 to 0.25) and fewer adverse events (RR 0.34, 95% CI 0.14 to 0.80). Herbal medicine plus active…

Study & population
Systematic review and meta-analysis of randomized trials in children with anorexia without organic disease.
Intervention
Herbal medicine was given as monotherapy or as an adjunct to other treatments for pediatric anorexia.
Key limitation
The evidence base was generally low to moderate quality, with high risk of bias and substantial heterogeneity in herbal formulations, comparators, and outcome measures.
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Original abstract

Background: Anorexia is a common obstacle to adequate nutrition in childhood, a critical period for physical growth. East Asian traditional medicine treatment modalities including herbal medicine (HM) a re considered an attractive therapeutic option,…