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Research paper

Gut microbial composition is altered in sarcopenia: A systematic review and meta-analysis of clinical studies

PLOS ONE
Q1
Aug 2024
Citations: 8
Influential: 0
Systematic Reviews / Meta-Analyses
83

Study answer

What this study found

Increasing evidence has shown that gut microbiota (GM) was involved in the pathophysiology of musculoskeletal disorders through multiple pathways such as protein anabolism, chronic inflammation and immunity, and imbalanced metabolism. We performed a systematic review and meta-analysis of human studies to evaluate GM diversity differences between individuals with and without sarcopenia, and explore bacteria with potential to become biomarkers. PubMed, Embase and Cochrane library were systematically searched from inception to February 16, 2024. Studies were included if they (1) sampled adults…

A separate results summary is not available, so this answer uses the paper abstract.

Study & population
Systematic Reviews / Meta-Analyses

Original abstract

Increasing evidence has shown that gut microbiota (GM) was involved in the pathophysiology of musculoskeletal disorders through multiple pathways such as protein anabolism, chronic inflammation and immunity, and imbalanced metabolism. We performed a …