Effect of cinnamon supplementation on glucose, lipids levels, glomerular filtration rate, and blood pressure of subjects with type 2 diabetes mellitus

Diabetology International

Jun 2016

DOI: 10.1007/s13340-015-0218-y

Citations: 47

Influential: 8

Interventional (Human) Studies

What this study found

Cinnamon supplementation was associated with improved glycemic, lipid, blood pressure, and kidney function outcomes versus placebo. Fasting plasma glucose, HbA1c, triglycerides, the TG/HDL-C ratio, and blood pressure decreased, while HDL-C and estimated glomerular filtration rate increased; end-of-study differences were reported as p < 0.005. No adverse effects were observed in the cinnamon group. Overall, the findings suggest cinnamon may help prevent or control diabetic complications in type 2 diabetes.

Study & population: 60-day placebo-controlled study in ambulatory adults with type 2 diabetes mellitus who were outpatients at Ladyao Hospital Diabetes Care Clinic in Nakonsawan Province, Thailand.
Intervention: Cinnamon capsules providing 1.5 g/day in total (three 500 mg capsules), taken orally three times daily after meals for 60 days, compared with placebo.
Key limitation: The active-arm sample was modest and the intervention lasted only 60 days, limiting confidence in long-term effects.

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Original abstract

No abstract is available for this paper.