Skip to content

Research paper

Comparative effectiveness of different antihypertensive agents in kidney transplantation: a systematic review and meta-analysis.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
May 2019
Citations: 39
Influential: 2
Systematic Reviews / Meta-Analyses
87

Study answer

What this study found

BACKGROUND We conducted a systematic review and meta-analysis to compare benefits and harms of different antihypertensive drug classes in kidney transplant recipients, as post-transplant hypertension (HTN) associates with increased cardiovascular (CV) morbidity and mortality. METHODS The Ovid-MEDLINE, PubMed and CENTRAL databases were searched for randomized controlled trials (RCTs) comparing all main antihypertensive agents versus placebo/no treatment, routine treatment. RESULTS The search identified 71 RCTs. Calcium channel blockers (CCBs) (26 trials) reduced the risk for graft loss {risk…

A separate results summary is not available, so this answer uses the paper abstract.

Study & population
Systematic Reviews / Meta-Analyses
View sourceOpen PDF

Original abstract

BACKGROUND We conducted a systematic review and meta-analysis to compare benefits and harms of different antihypertensive drug classes in kidney transplant recipients, as post-transplant hypertension (HTN) associates with increased cardiovascular (CV…