Oculplex Plus

• Vitamin A

  1500 mcg RAE

  Ingredient research · Vitamin A

  Vitamin A is an essential fat-soluble nutrient that enables normal vision, especially in dim light, and helps maintain immune defenses, skin and other epithelial tissues, growth, and reproduction. Supplementation can prevent or correct deficiency when intake or absorption is inadequate, benefiting visual, immune, and developmental health.

  • Supports maternal and breast-milk vitamin A status, particularly where baseline stores are low.
  • Supports hemoglobin response in some anemic or vitamin A-deficient populations, including when added to iron and folate.
  • Supports reducing bacterial-vaginosis incidence and prevalence during pregnancy and postpartum follow-up in a studied deficient setting.

  Top References

  • Efect of vitamin A suplementation: a systematic review.
  • Retinol-to-Fat Ratio and Retinol Concentration in Human Milk Show Similar Time Trends and Associations with Maternal Factors at the Population Level: A Systematic Review and Meta-Analysis.
  • Vitamin A supplementation for postpartum women.
  • Concomitant supplemental vitamin A enhances the response to weekly supplemental iron and folic acid in anemic teenagers in urban Bangladesh.
  • Weekly supplementation with iron and vitamin A during pregnancy increases hemoglobin concentration but decreases serum ferritin concentration in Indonesian pregnant women.
  • Maternal vitamin A and β-carotene supplementation and risk of bacterial vaginosis: a randomized controlled trial in rural Bangladesh.

• Vitamin C

  30 mg

  Ingredient research · Vitamin C

  Vitamin C is an essential water-soluble nutrient that supports collagen production, antioxidant defenses, and the normal function of immune cells. Supplementation reliably prevents or corrects deficiency, can improve absorption of plant-based iron, and may modestly shorten the duration of common colds when taken regularly.

  • Supports lower common-cold risk during brief periods of severe physical exercise or cold stress.
  • Supports circulating Vitamin C status across studied healthy and clinical populations.
  • Supports short-term blood-pressure and endothelial-function outcomes in studied adults.
  • Supports fasting-glucose and HbA1c outcomes in adults with type 2 diabetes.

  Top References

  • Vitamin C for preventing and treating the common cold.
  • Effect of Dietary or Supplemental Vitamin C Intake on Vitamin C Levels in Patients with and without Cardiovascular Disease: A Systematic Review
  • High-dose vitamin C supplementation increases skeletal muscle vitamin C concentration and SVCT2 transporter expression but does not alter redox status in healthy males.
  • Effects of vitamin C supplementation on blood pressure: a meta-analysis of randomized controlled trials.
  • Effect of vitamin C and vitamin E supplementation on endothelial function: a systematic review and meta-analysis of randomised controlled trials
  • Effects of vitamin C supplementation on glycaemic control: a systematic review and meta-analysis of randomised controlled trials
  • Effect of vitamin C on inflammation and metabolic markers in hypertensive and/or diabetic obese adults: a randomized controlled trial
  • Supplementation of Vitamin C Reduces Blood Glucose and Improves Glycosylated Hemoglobin in Type 2 Diabetes Mellitus: A Randomized, Double-Blind Study

• Vitamin E

  20 mg

  Ingredient research · Vitamin E

  Vitamin E is an essential fat-soluble antioxidant that protects cell membranes from oxidative damage and supports normal immune and nerve function. Supplementation is most useful for preventing or correcting deficiency, particularly when fat absorption is impaired; routine use has not shown broad protection against cardiovascular disease or cancer.

  • Supports improvement in liver histology in adults without diabetes who have biopsy-confirmed nonalcoholic steatohepatitis.
  • Supports lower CRP and malondialdehyde in studied adult populations, including people receiving hemodialysis.
  • Supports short-term improvements in fasting glucose and HbA1c in adults with type 2 diabetes.

  Top References

  • Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis.
  • The effect of vitamin E supplementation on selected inflammatory biomarkers in adults: a systematic review and meta-analysis of randomized clinical trials
  • The effects of vitamin E supplementation on malondialdehyde as a biomarker of oxidative stress in haemodialysis patients: a systematic review and meta-analysis
  • Effect of supplementation with tomato juice, vitamin E, and vitamin C on LDL oxidation and products of inflammatory activity in type 2 diabetes.
  • Antioxidant effects of vitamins in type 2 diabetes: a meta-analysis of randomized controlled trials

• Lutein

  10 mg

  Ingredient research · Lutein

  Lutein is a carotenoid that accumulates in the retina’s macula, where it helps filter high-energy light and protect tissue from oxidative stress. Supplementation can increase macular pigment and may support visual function, with greatest clinical relevance alongside other nutrients in formulations used for age-related macular degeneration.

  • Supports macular pigment density and selected contrast, glare, and retinal-sensitivity measures.
  • Supports attenuation of selected UV-induced skin-response markers in healthy adults.

  Top References

  • Clinical Effects of Dietary Supplementation of Lutein with High Bio-Accessibility on Macular Pigment Optical Density and Contrast Sensitivity: A Randomized Double-Blind Placebo-Controlled Parallel-Group Comparison Trial
  • Changes following supplementation with lutein and zeaxanthin in retinal function in eyes with early age-related macular degeneration: a randomised, double-blind, placebo-controlled trial
  • Molecular evidence that oral supplementation with lycopene or lutein protects human skin against ultraviolet radiation: results from a double‐blinded, placebo‐controlled, crossover study

• Zeaxanthin

  2 mg

  Ingredient research · Zeaxanthin

  Zeaxanthin is a carotenoid that accumulates in the macula, where it helps filter high-energy blue light and protect retinal tissue from oxidative stress. Supplementation can increase macular pigment and may support visual function and long-term eye health, particularly when dietary intake is low.

• Bilberry fruit extract(std. 25%)

  25 mg

  Ingredient research · Bilberry Extract

  Bilberry Extract is an anthocyanin-rich botanical supplement used mainly for eye and circulatory health, based on compounds that may influence antioxidant defenses and small blood vessels. It may modestly support eye comfort or visual function in some settings, but distinct benefits—especially improved night vision in healthy people—are not firmly established.

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