Folic Acid

• Folic Acid

  800 mcg DFE

  Ingredient research · Folic Acid

  Folic Acid is the synthetic, stable form of vitamin B9, needed for DNA synthesis, cell division, and healthy red blood cell formation. Supplementation reliably prevents or corrects folate deficiency and, when taken before conception and during early pregnancy, substantially lowers the risk of neural tube defects.

  • Supports folate status in women of reproductive age.
  • Supports healthy homocysteine levels.
  • Supports first-stroke prevention in adults with hypertension.
  • Supports endothelial-function measures in coronary artery disease.
  • Supports antidepressant response as an adjunct to fluoxetine, particularly in women.

  Top References

  • Folate Status of Reproductive Age Women and Neural Tube Defect Risk: The Effect of Long-Term Folic Acid Supplementation at Doses of 140 µg and 400 µg per Day
  • Folate status and homocysteine response to folic acid doses and withdrawal among young Chinese women in a large-scale randomized double-blind trial.
  • Weekly iron–folic acid supplements containing 2.8 mg folic acid are associated with a lower risk of neural tube defects than the current practice of 0.4 mg: a randomised controlled trial in Malaysia
  • Dose-dependent effects of folic acid on plasma homocysteine in a randomized trial conducted among 723 individuals with coronary heart disease.
  • Low-dose folic acid supplementation decreases plasma homocysteine concentrations: a randomized trial.
  • Folic acid supplementation on inflammation and homocysteine in type 2 diabetes mellitus: systematic review and meta-analysis of randomized controlled trials
  • Efficacy of folic acid therapy in primary prevention of stroke among adults with hypertension in China: the CSPPT randomized clinical trial.
  • Efficacy of folic acid supplementation on endothelial function and plasma homocysteine concentration in coronary artery disease: A meta-analysis of randomized controlled trials
  • Enhancement of the antidepressant action of fluoxetine by folic acid: a randomised, placebo controlled trial.

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