Research paper

Use of food frequency questionnaire to assess relationships between dietary habits and cardiovascular risk factors in NESCAV study: validation with biomarkers

Nutrition Journal

Nov 2013

DOI: 10.1186/1475-2891-12-143

Citations: 86

Influential: 5

Observational Studies (Human)

Study answer

What this study found

FFQ showed acceptable validity for ranking intakes of fruits/vegetables and several micronutrients. Energy adjustment generally improved correlations. Vitamin B9 had the strongest and most consistent correlations with biomarkers (serum folates and erythrocyte folates). Vitamin D correlations were modest and became non-significant after adjusting for supplement use. Vitamin B12 and Vitamin E correlations were mainly observed in women. Beta-carotene around 0.20; iodine around 0.10–0.23; iron and sodium showed weaker associations. Cross-classification indicated substantial within-quintile…

Study & population: Cross-sectional validation study within the NESCAV project; 922 adults (452 men, 470 women) aged 18–69 years; general population from the Wallonia region; FFQ estimates compared with nutritional biomarkers; analyses performed separately for men and women; three correlation models (crude, energy-adjusted model I, energy-adjusted model II);…
Key limitation: No recovery biomarkers; cross-sectional design; potential misreporting and supplement-use effects; 62 participants excluded due to incomplete supplement data; some nutrients show weak or inconsistent validity; results may be influenced by supplement use and seasonality.

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