Research paper
The Health Benefits of Probiotic Lactiplantibacillus plantarum: A Systematic Review and Meta-Analysis
Study answer
What this study found
Overall, L. plantarum supplementation showed beneficial effects in several condition-specific outcomes, but the effects were not uniform across all endpoints. In periodontal health, the meta-analysis favored intervention for pocket depth reduction, with a mean difference of 0.128 mm for all teeth sites and a significant benefit in periodontally diseased sites with pocket depth greater than 4 mm (p < 0.001); the all-sites analysis was also significant (p = 0.047). Abdominal pain improved in four studies (p < 0.001), and lipid outcomes also favored L. plantarum, with significant total…
- Study & population
- Systematic review and meta-analysis of human studies in individuals with pre-existing medical conditions, including both adults and children.
- Intervention
- Probiotic Lactiplantibacillus plantarum supplementation, given either alone or in combination with other strains, was evaluated versus control across randomized trials.
- Key limitation
- Findings were heterogeneous and appear strain- and disease-specific, which limits broad generalization across conditions.
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Open PDFOriginal abstract
To ensure effective administration of probiotics in clinical practice, it is crucial to comprehend the specific strains and their association with human health. Therefore, we conducted a systematic review and meta-analysis to evaluate the scientific …