Research paper
The effects of creatine supplementation on cognitive function in adults: a systematic review and meta-analysis
Study answer
What this study found
Creatine monohydrate supplementation may improve some cognitive domains in adults, especially memory, attention time, and information processing speed. It did not show a significant effect on overall cognitive function or executive function. Benefits appeared larger in people with health conditions, adults aged 18 to 60 years, and females, and short- and long-duration interventions did not differ meaningfully. Certainty of evidence was moderate for memory and low for other domains.
- Study & population
- Systematic review and meta-analysis of adult participants from multiple countries, including healthy adults and adults with various health conditions.
- Intervention
- Creatine monohydrate was the active supplement evaluated across included trials.
- Key limitation
- The evidence is limited by substantial variation in dose, duration, and study populations, along with generally small individual trials.
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Open PDFOriginal abstract
Background This study aimed to evaluate the effects of creatine monohydrate supplementation on cognitive function in adults and explore its potential role in preventing and delaying cognitive impairment-related diseases. Methods Following the PRISMA …