Research paper
Systematic Review on the Metabolic Interest of Glucosinolates and Their Bioactive Derivatives for Human Health
Citations: 31
Influential: 1
Systematic Reviews / Meta-Analyses
84
Study answer
What this study found
The consumption of glucosinolate-rich foods and their derivatives is linked to numerous health benefits, particularly in reducing cancer risk and modulating inflammation. The review encourages further research into their potential protective roles against various health conditions.
- Study & population
- The review includes 28 human intervention studies categorized by dietary sources of GSL, evaluating effects on various pathophysiological conditions.
- Intervention
- This systematic review focuses on the metabolism and bioavailability of glucosinolates (GSL) and their bioactive derivatives, particularly isothiocyanates (ITC), across multiple human studies.
- Key limitation
- Variability in individual responses, dietary habits, and the specific methodologies employed in the studies may impact the generalizability of findings.
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Open PDFOriginal abstract
In the last decade, most of the evidence on the clinical benefits of including cruciferous foods in the diet has been focused on the content of glucosinolates (GSL) and their corresponding isothiocyanates (ITC), and mercapturic acid pathway metabolit…