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Research paper

Shatavari Supplementation in Postmenopausal Women Improves Handgrip Strength and Increases Vastus lateralis Myosin Regulatory Light Chain Phosphorylation but Does Not Alter Markers of Bone Turnover

Nutrients
Q1
Sep 2021
Citations: 16
Influential: 1
Interventional (Human) Studies
87

Study answer

What this study found

Shatavari supplementation significantly improved handgrip strength while knee extensor strength showed no change. Myosin regulatory light chain phosphorylation increased, indicating potential benefits for muscle contractility. No effects on bone turnover markers were observed.

Study & population
Twenty-four postmenopausal women (≥60 years) completed a randomized, double-blind, placebo-controlled trial.
Intervention
Six-week supplementation with shatavari in postmenopausal women to assess its effects on muscle strength and markers of bone turnover.
Key limitation
Small sample size, lack of effects on knee extensor strength and bone turnover markers, and potential variability in muscle biopsy outcomes.
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Original abstract

Background: Shatavari has long been used as an Ayurvedic herb for women's health, but empirical evidence for its effectiveness has been lacking. Shatavari contains phytoestrogenic compounds that bind to the estradiol receptor, and may therefore benef…