Research paper
Reynoutria japonica Houtt for Acute Respiratory Tract Infections in Adults and Children: A Systematic Review
Study answer
What this study found
Herbal remedies containing Reynoutria japonica were associated with better symptom relief, but the evidence was very low quality. Symptom improvement rate favored the intervention across 7 trials and 1,013 participants (RR 1.14, 95% CI 1.09 to 1.20; I2 = 0%; p < 0.00001). Fever duration and Murray lung injury score were reduced in some comparisons. Adverse events did not differ significantly overall across 5 trials and 676 participants (RR 0.33, 95% CI 0.11 to 1.00; I2 = 0%; p = 0.05).
- Study & population
- Systematic review of 8 randomized controlled trials including 1,123 participants with acute respiratory tract infections.
- Intervention
- Across eight Chinese randomized trials, the active interventions were Reynoutria japonica-containing multi-herb formulas, most commonly Shufeng Jiedu Capsule (SFJDC), and also Tuire Liquid and Xuanfei Quyu Tongluo Liquid.
- Key limitation
- Overall certainty was very low because the included trials had poor methods and incomplete reporting.
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Open PDFOriginal abstract
Introduction: Respiratory tract infections (RTIs) are a major cause of morbidity and mortality in some high-risk groups including children and older adults. There is evidence that Chinese herbal medicine has an effect on RTIs. Reynoutria japonica Hou…