Red Yeast Rice for Hyperlipidemia: A Meta-Analysis of 15 High-Quality Randomized Controlled Trials
Citations:28
Influential Citations:1
Systematic Reviews / Meta-Analyses
84
COI
Enhanced Details
Methods
1,012 participants diagnosed with hyperlipidemia were included, with randomized controlled trials compared RYR to non-RYR interventions.
Intervention
Red Yeast Rice (RYR) was used alone or in combination with other therapies to treat hyperlipidemia.
Results
RYR was found effective in lowering total cholesterol, triglycerides, and LDL-C while raising HDL-C levels. RYR showed a significant positive effect when compared to nutraceuticals and placebo, but was less effective than statins in lowering TC.
Limitations
Limited high-quality RCTs available, potential methodological defects in trials, and high heterogeneity in results due to variations in RYR products.
Abstract
Background: RYR is a commonly used lipid-lowering dietary supplements in Asian and European countries, showing considerable benefits and low toxicity. This quantitative study aims to present high-quality evidence regarding the efficacy and safety of ...