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Research paper

Randomised trial of coconut oil, olive oil or butter on blood lipids and other cardiovascular risk factors in healthy men and women

BMJ Open
Q1
Mar 2018
Citations: 157
Influential: 8
Interventional (Human) Studies
90

Study answer

What this study found

Butter increased LDL-C more than coconut oil and olive oil over 4 weeks (approx +0.38–0.42 mmol/L); coconut oil did not differ from olive oil for LDL-C and slightly lowered LDL-C vs baseline. Coconut oil significantly increased HDL-C compared with butter or olive oil. Butter increased TC/HDL-C ratio and non-HDL-C versus coconut oil. No significant differences between groups for weight, BMI, central adiposity, fasting glucose or blood pressure; coconut oil reduced C-reactive protein vs olive oil. In practical terms, olive oil remains favorable for LDL-C; coconut oil behaves more like olive…

Study & population
Randomised parallel-group clinical trial conducted in the general community in Cambridgeshire, UK (June–July 2017).
Intervention
Consume 50 g daily for 4 weeks of one of: extra virgin coconut oil, unsalted butter, or extra virgin olive oil; may be substituted for other fats or taken as a supplement within usual diet.
Key limitation
Short 4-week duration; not blinded to the intervention; pragmatic design with no control of total energy intake; no objective biomarker of fat adherence (no blood fatty acid profiling); highly selected BBC-recruited volunteers which may limit generalisability; results address intermediate lipid markers rather than…
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Original abstract

Introduction High dietary saturated fat intake is associated with higher blood concentrations of low-density lipoprotein cholesterol (LDL-C), an established risk factor for coronary heart disease. However, there is increasing interest in whether vari…