Protective and Recovery Effects of Resveratrol Supplementation on Exercise Performance and Muscle Damage following Acute Plyometric Exercise

Study answer

What this study found

RES supplementation, especially at 1000 mg/day, reduced PEIMD-related muscle damage and soreness and accelerated recovery of explosive and anaerobic performance. CK decreased by about 19–26% at 24 h and 30–39% at 48 h in RES-500 and RES-1000 vs placebo; LDH decreased by about 12% at 2 h in RES-1000. Pain thresholds (PPT) increased in RES groups at 24 h (vastus lateralis 1.30–1.41x) and 72 h (vastus medialis 1.68x for RES-1000). Wingate results at 24 h were ~11% higher for RES-1000 vs placebo. Vertical jump height showed no protective effect. No adverse effects on liver or kidney function…

Study & population

Double-blind, placebo-controlled randomized trial with 36 healthy, young, non-athletic male participants (mean age ~21.1 years; height ~173 cm; weight ~70 kg).

Intervention

Trans-resveratrol supplementation for 10 days around PEIMD: RES-500 group received 500 mg/day RES with a matching 500 mg/day methylcellulose as vehicle; RES-1000 group received 1000 mg/day RES; Placebo group received 1000 mg/day methylcellulose.

Key limitation

Male-only, non-athlete sample; small size; short-term follow-up; not standardized diet; results may not generalize to women, athletes, or other populations.

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Original abstract