Research paper
Omega 6 fatty acids for the primary prevention of cardiovascular disease.
Study answer
What this study found
No cardiovascular event data were available. Increasing omega-6 intake did not show consistent effects on blood pressure or lipid levels, and decreasing omega-6 intake likewise showed no clear benefit across the small trials. Examples of reported 24-week results included modest within-group changes in systolic and diastolic blood pressure and mixed, small changes in total cholesterol, LDL cholesterol, HDL cholesterol, and triglycerides, without a consistent direction across studies. Overall, evidence was very limited and at risk of bias, so firm conclusions about cardiovascular benefit or…
- Study & population
- Systematic review of randomized primary-prevention trials in adults without established cardiovascular disease.
- Intervention
- Across the included randomized trials, omega-6 intake was altered by providing specific foods, spreads, and oils or by giving CLA capsules.
- Key limitation
- Evidence came from only a small number of short trials with 664 participants in total and 24-week follow-up.
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Open PDFOriginal abstract
BACKGROUND Omega 6 plays a vital role in many physiological functions but there is controversy concerning its effect on cardiovascular disease (CVD) risk. There is conflicting evidence whether increasing or decreasing omega 6 intake results in benefi…