Manipulation of starch bioaccessibility in wheat endosperm to regulate starch digestion, postprandial glycemia, insulinemia, and gut hormone responses: a randomized controlled trial in healthy ileostomy participants12

Study answer

What this study found

Coarse porridge produced a clearly better postprandial metabolic profile than smooth porridge. Compared with smooth porridge, 120-min incremental AUCs were reduced by 33% for glucose, 43% for insulin, 40% for C-peptide, and 50% for GIP, all with P < 0.01. Peak glucose, insulin, C-peptide, and GIP were also higher after smooth than coarse porridge by 12%, 32%, 37%, and 60%, respectively. GLP-1 and PYY rose after both meals but did not differ significantly, and ileal resistant starch recovery was similar for both meals at about 3 g over 10 h. The authors concluded that preserving wheat…

Study & population

Randomized crossover trial in healthy adult ileostomy participants in London, United Kingdom.

Intervention

Two oral porridge test meals based on durum wheat endosperm were compared in a randomized crossover design: coarse porridge with intact endosperm particles (about 2 mm) versus smooth porridge with finely milled particles (<0.2 mm).

Key limitation

Very small acute crossover study with only 9 analyzed participants per arm, limiting precision and generalizability.

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Original abstract