Research paper
Insights into the cardiovascular benefits of taurine: a systematic review and meta-analysis
Study answer
What this study found
Taurine supplementation was associated with overall cardiovascular benefit. Pooled analyses showed significant reductions in heart rate, systolic blood pressure, diastolic blood pressure, and NYHA functional class, along with improvement in left ventricular ejection fraction. The most pronounced effects were seen in heart failure patients, and subgroup analyses also showed heart rate reductions in heart failure and healthy individuals, systolic blood pressure reductions in healthy individuals, heart failure, and other disease groups, and diastolic blood pressure reductions in hypertensive…
- Study & population
- This was a systematic review and meta-analysis of 20 randomized trials conducted between 1985 and 2021.
- Intervention
- Taurine was administered in the included active arms as capsules, tablets, or solution, usually once daily, at doses ranging from 0.5 g/day to 6 g/day.
- Key limitation
- The evidence is limited by substantial clinical heterogeneity across populations, conditions, doses, and treatment durations, with active-arm sample sizes often small.
View source
Open PDFOriginal abstract
Cardiovascular disease (CVD) remains the foremost cause of mortality globally. Taurine, an amino acid, holds promise for cardiovascular health through mechanisms such as calcium regulation, blood pressure reduction, and antioxidant and anti-inflammat…