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Research paper

Inorganic nitrate and beetroot juice supplementation reduces blood pressure in adults: a systematic review and meta-analysis.

The Journal of nutrition
Q1
Jun 2013
Citations: 366
Influential: 23
Systematic Reviews / Meta-Analyses
93

Study answer

What this study found

Overall, inorganic nitrate and beetroot juice supplementation reduced systolic blood pressure, while the effect on diastolic blood pressure was smaller and less consistent. Pooled systolic BP decreased by 4.4 mm Hg (95% CI 5.9 to 2.8; P < 0.001), whereas diastolic BP decreased by 1.1 mm Hg (95% CI 2.2 to 0.1; P = 0.06). Beetroot juice and inorganic nitrate showed similar systolic BP effects, with reductions of 4.5 mm Hg and 4.2 mm Hg, respectively; diastolic effects were not significant for either intervention. Higher daily inorganic nitrate dose appeared to be associated with greater…

Study & population
Systematic review and meta-analysis of 16 randomized clinical trials including 254 adults with crossover designs.
Intervention
Oral beetroot juice or inorganic nitrate supplementation, typically given daily in short-term randomized crossover trials against placebo.
Key limitation
Evidence was based on small, short-duration crossover trials, many of which enrolled mostly healthy young men.
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Original abstract

Diets including food products rich in inorganic nitrate are associated with lower blood pressure (BP). The evidence for the BP-lowering effects of inorganic nitrate and beetroot in randomized clinical trials has not been systematically assessed. The …