Improving Antioxidant Capacity in Children With Autism: A Randomized, Double-Blind Controlled Study With Cysteine-Rich Whey Protein
Citations:14
Influential Citations:1
Interventional (Human) Studies
90
Enhanced Details
Methods
46 preschool children with confirmed autism spectrum disorder (ASD) participated in a randomized, double-blind, placebo-controlled trial, with 21 receiving CRWP and 19 receiving a rice protein placebo.
Intervention
A 90-day intervention using cysteine-rich whey protein (CRWP) to improve glutathione levels and ASD behaviors in children aged 3-5 years.
Results
Improvements were noted in glutathione levels and several behavioral assessments, particularly in the Vineland Adaptive Behavior Scale, indicating a significant positive effect from CRWP supplementation.
Limitations
The small sample size and short duration of the intervention limit generalizability. Future studies are needed with larger populations and longer follow-ups.
Abstract
Previous studies indicate that children with autism spectrum disorder (ASD) have lower levels of glutathione. Nutritional interventions aim to increase glutathione levels suggest a positive effect on ASD behaviors, but findings are mixed or non-signi...