Research paper
Folic acid supplementation during pregnancy for maternal health and pregnancy outcomes.
Study answer
What this study found
BACKGROUND During pregnancy, fetal growth causes an increase in the total number of rapidly dividing cells, which leads to increased requirements for folate. Inadequate folate intake leads to a decrease in serum folate concentration, resulting in a decrease in erythrocyte folate concentration, a rise in homocysteine concentration, and megaloblastic changes in the bone marrow and other tissues with rapidly dividing cells OBJECTIVES To assess the effectiveness of oral folic acid supplementation alone or with other micronutrients versus no folic acid (placebo or same micronutrients but no folic…
A separate results summary is not available, so this answer uses the paper abstract.
- Study & population
- Systematic Reviews / Meta-Analyses
Original abstract
BACKGROUND During pregnancy, fetal growth causes an increase in the total number of rapidly dividing cells, which leads to increased requirements for folate. Inadequate folate intake leads to a decrease in serum folate concentration, resulting in a d…