Research paper
Effects of propolis consumption on blood pressure, lipid profile and glycemic parameters in adults: a GRADE-assessed systematic review and dose–response meta-analysis
Study answer
What this study found
Propolis was associated with favorable changes in several cardiometabolic outcomes, especially triglycerides, LDL-cholesterol, HDL-cholesterol, fasting glucose, HbA1c, insulin, HOMA-IR, and systolic blood pressure. In the pooled analysis, TAG fell by WMD -10.44 mg/dl (95% CI -16.58, -4.31; P = 0.001), LDL-cholesterol by -9.31 mg/dl (95% CI -13.50, -5.12; P < 0.001), HDL-cholesterol increased by 2.03 mg/dl (95% CI 0.24, 3.83; P = 0.02), and SBP decreased by -2.24 mmHg (95% CI -4.08, -0.39; P = 0.01). There was no significant effect on total cholesterol or diastolic blood pressure. The authors…
- Study & population
- Systematic review and dose-response meta-analysis of randomized controlled trials in adults with a range of health statuses, including healthy participants and patients with type 2 diabetes, dyslipidemia, NAFLD, chronic kidney disease, metabolic syndrome, PCOS, rheumatoid arthritis, obesity, and related conditions.
- Intervention
- Oral propolis was tested across the included randomized trials in capsules, tablets, pills, solutions, or drops.
- Key limitation
- Substantial heterogeneity was present for several outcomes, with I2 values often high, reflecting variability in propolis preparations, doses, populations, and study designs.
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Open PDFOriginal abstract
Abstract Propolis, as a by-product of honey production, has shown several beneficial effects on cardiovascular risks in past randomised controlled trials, although the findings are not conclusive. In this review, we intend to evaluate the effects of …