Research paper

Effects of curcumin and/or coenzyme Q10 supplementation on metabolic control in subjects with metabolic syndrome: a randomized clinical trial

Nutrition Journal

Oct 2022

DOI: 10.1186/s12937-022-00816-7

Citations: 29

Influential: 2

Interventional (Human) Studies

COI

Study answer

What this study found

Curcumin improved lipid parameters, while coenzyme Q10 alone and the curcumin plus coenzyme Q10 combination did not produce meaningful benefits on metabolic syndrome components. In the curcumin arm, triglycerides fell by −58.0 ± 49.1 (P < 0.001), HDL cholesterol rose by 10.0 ± 5.3 (P < 0.001), total cholesterol fell by −30.9 ± 35.1 (P < 0.001), and LDL cholesterol fell by −14.1 ± 6.2 (P < 0.001). In the coenzyme Q10 arm, triglycerides changed by −9.8 ± 30.4 (P = 0.08) and total cholesterol by −10.1 ± 30.2 (P = 0.06), with no significant changes in blood pressure, waist circumference, or…

Study & population: Randomized clinical trial in adults with metabolic syndrome diagnosed by IDF criteria in Tehran, Iran.
Intervention: This 12-week randomized clinical trial tested oral curcumin and coenzyme Q10 in adults with metabolic syndrome.
Key limitation: Small active-arm sample size (22 per group) and short 12-week duration limit certainty and longer-term inference.

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Original abstract

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