Research paper
Effects of calcium supplementation on lipids, blood pressure, and body composition in healthy older men: a randomized controlled trial.
The American journal of clinical nutrition
Q1
Citations: 111
Influential: 6
Interventional (Human) Studies
86
Study answer
What this study found
Overall, calcium supplementation did not improve serum lipids, blood pressure, or body composition in healthy older men. The primary endpoint, change in the HDL to LDL cholesterol ratio, showed no significant treatment effect (P = 0.47), and there were no significant between-group differences for LDL, HDL, total cholesterol, HDL to total cholesterol ratio, triglycerides, blood pressure, soft tissue mass, or weight (lipids P > 0.28; blood pressure P > 0.60; fat mass P = 0.45; lean mass P = 0.33; weight P = 0.83). Post hoc subgroup analyses in men with baseline dietary calcium intake below 785…
- Study & population
- Randomized controlled trial in generally healthy older men in Australia.
- Intervention
- Calcium citrate was given as elemental calcium 600 mg once daily in the evening (Ca600) or 600 mg twice daily for 1200 mg/day (Ca1200) for 2 years, compared with placebo.
- Key limitation
- The main results were null, and the apparent blood pressure benefit came from post hoc subgroup analyses rather than the primary comparison.
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