Skip to content

Research paper

Effects of a diet based on inulin-rich vegetables on gut health and nutritional behavior in healthy humans

The American Journal of Clinical Nutrition
Q1
Apr 2019
Citations: 158
Influential: 10
Interventional (Human) Studies
85

Study answer

What this study found

The ITF-rich vegetable diet was feasible and generally well tolerated, and it produced a transient increase in Bifidobacterium along with improved satiety and reduced desire for sweet and salty foods. Bifidobacterium increased 3.8-fold by sequencing and 3.0-fold by qPCR, with Bifidobacterium longum subsp. longum also increasing; these microbial changes returned toward baseline about 3 weeks after the intervention ended. Flatulence increased during the diet, but other gastrointestinal symptoms were largely unchanged, and in vivo hydrogen breath testing was not modified. The intervention also…

Study & population
Single-group, within-subject intervention in healthy adult volunteers at Université catholique de Louvain in Louvain-la-Neuve, Belgium.
Intervention
Participants followed a 2-week diet based on inulin-type fructan rich vegetables, providing at least 9 g fructans per day and averaging 15 g/day from Jerusalem artichoke, salsify, artichoke, leek, onion, and garlic; the foods were eaten daily as meals and soup.
Key limitation
The study was small, short, and single-group with participants serving as their own controls, so causal inference is limited.
View sourceOpen PDF

Original abstract

ABSTRACT Background Inulin-type fructans (ITFs) are a type of fermentable dietary fiber that can confer beneficial health effects through changes in the gut microbiota. However, their effect on gut sensitivity and nutritional behavior is a matter of …