Research paper
Dietary Magnesium Intake and Metabolic Syndrome in the Adult Population: Dose-Response Meta-Analysis and Meta-Regression
Study answer
What this study found
Dietary magnesium intake is inversely associated with metabolic syndrome. The pooled RR for a 150 mg/day increase is 0.88 (95% CI 0.84-0.93) with moderate heterogeneity (I2 = 36.3%). The relationship appears linear across intake levels, with higher magnesium intake linked to lower metabolic syndrome risk. Authors suggest focusing on magnesium-rich foods rather than supplements and call for longitudinal studies and randomized trials to establish causality and evaluate supplementation.
- Study & population
- Meta-analysis of observational studies (10 articles: 8 cross-sectional, 2 prospective cohorts) including 30,092 participants.
- Key limitation
- Moderate heterogeneity across studies (I2 36.3%); variability in dietary magnesium assessment methods (FFQ, 24-hour recalls, and 3-day records); residual confounding inherent to observational designs; exposure measured primarily at baseline; data for higher intake levels (>450 mg/day) were sparse; cannot assess…
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Open PDFOriginal abstract
Increasing evidence has suggested an association between dietary magnesium intake and metabolic syndrome. However, previous research examining dietary magnesium intake and metabolic syndrome has produced mixed results. Our objective was to determine …