Research paper
Dietary interventions for adults with chronic kidney disease.
Study answer
What this study found
Dietary interventions showed uncertain effects on hard kidney and survival outcomes, but some trials suggested improvements in quality of life, blood pressure, eGFR, serum albumin, and LDL cholesterol. In pooled analyses, all-cause mortality was inconclusive (RR 1.59, 95% CI 0.60 to 4.21), as was progression to end-stage kidney disease (RR 0.53, 95% CI 0.26 to 1.07). Health-related quality of life improved in two studies (MD 11.46, 95% CI 7.73 to 15.18), and pooled effects favored lower systolic blood pressure (MD -9.26 mm Hg) and higher serum albumin (MD 0.16 g/dL). Overall, the authors…
- Study & population
- Systematic review of 17 studies involving 1639 adults with chronic kidney disease at any stage, including people on dialysis and kidney transplant recipients.
- Intervention
- This review evaluated a range of oral dietary interventions rather than a single supplement regimen.
- Key limitation
- Evidence quality was very low, with high or unclear risk of bias across studies.
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Open PDFOriginal abstract
BACKGROUND Dietary changes are routinely recommended in people with chronic kidney disease (CKD) on the basis of randomised evidence in the general population and non-randomised studies in CKD that suggest certain healthy eating patterns may prevent …