Research paper
Conjugated linoleic acid supplementation for 1 y reduces body fat mass in healthy overweight humans.
Study answer
What this study found
Long-term CLA supplementation reduced body fat mass compared with placebo, with similar fat-loss effects for CLA-free fatty acid and CLA-triacylglycerol. From month 0 to 12, body fat mass changed by 0.2 kg with placebo, -1.7 kg with CLA-free fatty acid, and -2.4 kg with CLA-triacylglycerol; body fat mass was significantly lower in both CLA groups versus placebo at 12 months (P = 0.001). CLA-free fatty acid also increased lean body mass relative to placebo, with a 0.7 kg increase versus 0.0 kg and 1.8% greater lean body mass than placebo (P = 0.002), and lean body mass was significantly…
- Study & population
- Randomized, double-blind, placebo-controlled trial in healthy overweight adults in Norway.
- Intervention
- Participants received oral conjugated linoleic acid for 12 months as 6 softgel capsules daily.
- Key limitation
- The trial was modest in size, with about 60 participants per active arm, and it was conducted in a single country, which may limit generalizability.
View source
Open PDFOriginal abstract
BACKGROUND Short-term trials showed that conjugated linoleic acid (CLA) may reduce body fat mass (BFM) and increase lean body mass (LBM), but the long-term effect of CLA was not examined. OBJECTIVE The objective of the study was to ascertain the 1-y …