Research paper
Clinical Effects of L-Carnitine Supplementation on Physical Performance in Healthy Subjects, the Key to Success in Rehabilitation: A Systematic Review and Meta-Analysis from the Rehabilitation Point of View
Citations: 19
Influential: 0
Systematic Reviews / Meta-Analyses
82
Study answer
What this study found
L-carnitine supplementation significantly increased serum total and free carnitine levels and VO2 at rest. However, no significant effect on plasma lactate levels at rest or after exercise was observed. The effective dosage for improvements was 2 g/dL for specific durations.
- Study & population
- Included randomized controlled trials, retrospective and prospective studies of healthy adults and athletes who supplemented with L-carnitine.
- Intervention
- The meta-analysis focused on the effects of L-carnitine supplementation on physical performance and metabolic parameters in healthy adults, including elderly individuals and athletes.
- Key limitation
- Heterogeneity in sample characteristics and limited data on optimal dosing for metabolic changes and physical performance outcomes.
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Open PDFOriginal abstract
L-carnitine supplementation improves body strength, sports endurance and exercise capacity, as well as delaying the onset of fatigue. The aim of this study was to identify the correct dosage of supplementation to obtain improvements in physical perfo…