Research paper
A whey protein-based multi-ingredient nutritional supplement stimulates gains in lean body mass and strength in healthy older men: A randomized controlled trial
Study answer
What this study found
Twice-daily supplementation increased lean mass and strength in healthy older men, and adding structured exercise further enhanced strength gains, especially for the upper body. During weeks 0-6, isotonic strength increased by +14 ± 4 kg with the supplement versus +3 ± 2 kg with control (P < 0.001), and lean body mass increased by +1.2 ± 0.3 kg versus -0.1 ± 0.2 kg (P < 0.001). By the end of the study, upper body strength was 119 ± 4 kg in the supplement group versus 109 ± 5 kg in controls (P = 0.039). There were significant group-by-time interactions for whole body lean mass (P < 0.01),…
- Study & population
- Randomized controlled trial in healthy older men from Canada, all non-diabetic at screening.
- Intervention
- Participants in the active arm consumed two drinks daily for 20 weeks.
- Key limitation
- The trial enrolled only healthy older men, limiting generalizability to women, younger adults, or clinical populations.
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Open PDFOriginal abstract
Protein and other compounds can exert anabolic effects on skeletal muscle, particularly in conjunction with exercise. The objective of this study was to evaluate the efficacy of twice daily consumption of a protein-based, multi-ingredient nutritional…