Research paper
A Randomized Trial of Vitamin E Supplementation and Cognitive Function in Women
Study answer
What this study found
Herbal regimens did not reduce vasomotor symptoms vs placebo over 12 months. The average difference in daily vasomotor symptoms between placebo and herbal regimens was <1 symptom/day at 3 months and <0.6/day across follow-up. Hormone therapy substantially reduced vasomotor symptoms vs placebo (≈4.5 fewer symptoms/day at 3 months and ≈4 fewer/day across follow-ups). Wiklund subscale improved with hormone therapy but not with herbal regimens. Adverse events more common with hormone therapy included breast pain and menstrual disorders; rare cancers occurred (endometrial cancer in multibotanical…
- Study & population
- Design: 1-year double-blind, randomized, controlled trial conducted at Group Health, Washington.
- Intervention
- Black cohosh: 160 mg daily; Actaea racemosa or Cimicifuga racemosa; 2.5% triterpene glycosides; 70% ethanol extract; delivered in capsules; duration 12 months.
- Key limitation
- Population largely white and well-educated; limited generalizability to diverse populations.
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Open PDFOriginal abstract
The following abstracts of articles from leading journals have been selected on the basis of their importance to the practice of obstetrics and gynecology. Factors Influencing Adverse Perinatal Outcomes in Pregnancies Achieved Through Use of In Vitro…