Research paper
A Fully Automated Web-Based Program Improves Lifestyle Habits and HbA1c in Patients With Type 2 Diabetes and Abdominal Obesity: Randomized Trial of Patient E-Coaching Nutritional Support (The ANODE Study)
Study answer
What this study found
ANODE improved dietary quality and produced clinically relevant weight loss and glycemic benefits versus usual care over 16 weeks. Diet quality (DQI-I) increased by 4.55 points in the intervention vs -1.68 in control (P<0.01). Weight and waist circumference decreased more with ANODE; HbA1c improved; a higher proportion achieved >3% weight loss (33.3% vs 6.7%) and >5% weight loss (20.0% vs 3.3%). No significant differences in blood pressure, lipids, liver enzymes, fasting glucose, hs-CRP, or VO2 max overall; per-protocol analysis suggested possible VO2 max improvement. Self-reported physical…
- Study & population
- Design: 16-week, open-label, randomized, 1:1 parallel-arm trial conducted at two university hospitals in Paris, France.
- Key limitation
- Short follow-up (16 weeks); small sample (n=120); open-label design; two recruitment centers; lack of objective trackers for physical activity.
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Open PDFOriginal abstract
Background The prevalence of abdominal obesity and type 2 diabetes mellitus (T2DM) is a public health challenge. New solutions need to be developed to help patients implement lifestyle changes. Objective The objective of the study was to evaluate a f…